Underpinning the importance of understanding the nucleotide context preferences of base editors, during the final preparations of this manuscript, Arbab & Shen et al. performed a comprehensive base editor target library analysis to elucidate the determinants of base editing outcomes40. With this data t...
Limited population and cohort studies in the U.S. have shown variable VS rates at 3 to 8 months of 50-85% and rebound at 3 years of 20-50% [26,27]. Outside the U.S., several cohorts with universal access to healthcare have demon- strated a remarkable response to HAART when com...