高通量筛选(High throughput screening,HTS)技术是指以分子水平和细胞水平的实验方法为基础,以微板形式作为实验工具载体,以自动化操作系统执行试验过程,以灵敏快速的检测仪器采集实验结果数据,以计算机分析处理实验数据,在同一时间检测数以千万的样品,并以得到的相应数据库支持运转的技术体系,它具有微量、快速、灵敏和准确...
How can the automated dispensing of chemicals improve the safety of my lab? What is “Design of Experiment” (DoE) and how can it improve my reaction screening? How can I analyze my reaction data? How many samples can be run in a parallel reaction screening?
High-throughput experimentrare-event ruptureWeibull distributionfatigueThe conditions for rupture of a material commonly vary from sample to sample, and depend on the types of loads, such as monotonic or cyclic loads. Of great impodoi:10.2139/ssrn.3891790Zhou, Yifan...
and P.S. designed the research. X.L. performed the high-throughput screening and analyzed the data. X.D. and X.W. developed the computational tools and performed the informatic analysis. J.U. and C.J. performed and analyzed the behavioral validation experiment. W.N.Z., C.J., and S...
High-throughput experiments enable the systematic investigation of thousands of sequences in a single experiment. Multiple technologies have been developed including those based on synthetic library designs such as massively parallel reporter assays and those based on genome-fragmentation approaches such as ...
In conclusion, we introduce here MR-BMA, the first approach to perform risk factor selection in multivariable MR, which can identify causal risk factors from a high-throughput experiment. MR-BMA can be used to determine which out of a set of related risk factors with common genetic predictors...
ApplicationsVariousMore experiment design/Screen more assays High content imaging pipeline and workflow High content imaging and high throughput analysis platforms are designed for exceptional resolution with subcellular, automated detection, and phenotyping with intact, fixed, or live organisms. A typical hi...
Proteinarraysprovideapowerfultoolforthehighthroughputparallelanalysisof thousands ofproteinswithin asingleexperiment. 蛋白质芯片为高通量并行分析和检测蛋白质提供了强有力的工具。 www.chemyq.com 8. High-throughputtargetdiscoveryconfrontsthe biopharmaceuticalindustrywithaplethoraoftargetcandidates. ...
关键词: Analysis of substances experiment Cellular biology Euphoric mood functional genomics DOI: 10.1016/j.copbio.2003.11.001 被引量: 435 年份: 2004 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 Elsevier (全网免费下载) Elsevier 掌桥科研 万方医学 Ingenta 查看更多 相似文献 参考文献 ...
While the interpretation of the outcome of a standard experiment used to depend on the knowledge of one human expert from the field, today's screening tools produce data quantities not manageable by human inspection. After receiving a list of differentially regulated genes from a microarray gene ...