B-cell aggressive lymphomaHigh-grade B-cell lymphomadouble hit lymphomaintensive chemoimmunotherapyIntroduction: High Grade B-cell Lymphomas (HGBL) have been defined as a new separate entity in the 2016 revised WHO classification of lymphoid neoplasms. The previously well-known Double- and Triple-Hit...
We describe 13 patients with TdT-positive aggressive B-cell lymphoma. The clinicopathologic features of these patients were highly heterogeneous, but for the purpose of this study we grouped these cases as follows: (1) de novo high-grade B-cell lymphoma with,, and/orrearrangements (double-hit ...
Patients with MYC/BCL2 double-hit lymphoma (DHL) are known to have an aggressive clinical course and to respond poorly to various therapies including intensive chemotherapy and stem cell transplant. Less is known about high-grade B-cell lymphoma with MYC rearrangement without concomitant BCL2 and ...
High-grade B-cell lymphoma of the peritoneum as a result of transformation of a CD5-negative monoclonal B lymphocytosis population in a patient with myelodysplastic syndrome treated with 5-azacytidineHigh-grade B-cell lymphoma of the peritoneum as a result of transformation of a CD5-negative monoc...
Aggressive B cell Lymphoma: Optimal Therapy for MYC-positive, Double-Hit, and Triple-Hit DLBCL Double-hit and triple-hit lymphomas harbor concurrent rearrangements of MYC and BCL2 and/or BCL6 and are also associated with a very aggressive course ... Dunleavy,Kieron - 《Current Treatment Options...
High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology Author links open overlay panelDavid W. Scott 1, 2, Rebecca L. King 3, Annette M. Staiger 4, 5, Susana Ben-Neriah 1, Aixiang Jiang 6, Heike Horn 5, Anja Mottok ...
High-grade B-cell lymphoma (HGBL), not otherwise specified (NOS), is a recently introduced diagnostic category for aggressive B-cell lymphomas. It includes tumors with Burkitt-like or blastoid morphology that do not have double-hit cytogenetics and that cannot be classified as other well-defined...
Interestingly, molecular biological analyses revealed that CLL cells were of the T-cell type, whereas lymphoma cells were of the B-cell type. Chemotherapy using the L-VCA short protocol was effective for 155 days, but the dog died on day 194 after diagnosis, despite rescue therapies. 展开 ...
High-grade B cell lymphoma, unclassifiable, with blastoid features: an unusual morphological subgroup associated frequently with BCL2 and/or MYC gene rearr... AIMS: A subset of B cell lymphomas with blastoid features do not fit either as B lymphoblastic lymphoma/leukaemia or blastoid mantle cel...
Herein, we present an elderly patient with a diagnosis of high-grade B-cell lymphoma, in whom a complete response was observed after prolonged COVID-19 infection. Case summary An 81-year-old female patient received her first cycle of R-CHOP (rituximab, cyclophosphamide, vincristine, and ...