Ahematocrit(HCT) test, also known as the packed-cell volume (PCT), measures how much of your blood consists ofred blood cells. Red blood cells carry oxygen from your lungs throughout your body. A low HCT could be due toanemia, a vitamin or mineral deficiency, or blood loss. Having too...
MD JAMA Comment & Response High- vs Low-Dose Tranexamic Acid Infusion and Need for Red Blood Cell Transfusion and Adverse Events in Cardiac Surgery Andreas Koster, MD, PhD; Nikolai Hulde, MD; Armin Zittermann, PhD JAMA Key Points Question Among patients undergoing cardiac surgery with cardiopul...
A low platelet count, one of parameters of portal hypertension, is clinically a predictor of postoperative mortality, while platelets induce tumor development during growth factor secretion. In this study, we retrospectively investigated whether high platelet count negatively affects the survival of patient...
Preincubation of platelets with NH 4Cl (10 mM, 2 h), followed by thrombin stimulation, results in secretion of all β-hexosaminidase as a low-uptake form. The data support the hypothesis that there are secretory and nonsecretory forms of lysosomes. The secretory lysosomes would contain low-...
A CBC measures the concentration of white blood cells, red blood cells, platelets in the blood, and aids in diagnosing conditions and disease such as malignancy, anemia, or blood clotting problems. Eczema and Atopic Dermatitis Rashes Slideshow Eczema is a common allergic skin condition. Learn ...
A very low CTGF amount was secreted from platelets at low shear stress (11.4 +/- 3.9% of total CTGF in platelets). On the contrary, high shear stress caused a markedly increased CTGF release from platelets (29 +/- 13.8%, p = 0.07 vs low shear stress, n = 4). Immunohistochemical ...
Binding of apoE-rich high density lipoprotein particles by saturable sites on human blood platelets inhibits agonist-induced platelet aggregation. High density lipoproteins (HDL, d 1.063-1.21 g/ml) are reported to stimulate, to have no effect on, or to inhibit agonist-induced platelet aggregation....
In an analysis of the IMPROVE-IT trial that compared ezetimibe with placebo in patients with ACS treated with simvastatin [36], high FS (>0.67, n=2,106) vs low FS (<-1.455, n=5,440) was associated with 30% increased risk of MACE. Analogous to the findings for apabetalone in the ...
In addition, a higher pre-operative level of platelets was associated with a higher risk of stroke (p = 0.034). In this study we found no significant association between recurrent surgeries and the risk of stroke (p = 0.746). However, after a multivariate analysis for potential ...
Platelets and lipoproteins play a crucial role in atherogenesis, in part by their ability to modulate inflammation and oxidative stress. While oxidized low density lipoproteins (OxLDL) play a central role in the development of this disease, high density lipoproteins (HDL) represent an atheroprotective...