Furthermore, research has shown a correlation between high uric acid levels and type 2 diabetes, high blood pressure, and fatty liver disease. High uric... CL Chen - 《Tungs Medical Journal》 被引量: 0发表: 2022年 Acute induction of psoriasis-like skin inflammation disturbes vascular tone an...
Epigallocatechin gallate reduces uric acid levels by regulating xanthine oxidase activity and uric acid excretion in vitro and in vivo. Ann. Palliat. Med. 9, 331–338. https://doi.org/10.21037/apm.2019.11.28 (2020). Article PubMed Google Scholar Xu, X. Y. et al. Effects and mechanisms...
Serum creatinine levels were measured in all participants since 2012. Statistical analysis Data are presented as mean ± standard deviation. The statistical significance of differences in means was analysed using the Student’s t-test. Statistical significance was set at P < 0.05 for all ...
In humans and other higher primates, uric acid is the final compound of purines catabolism, but all other mammals converts uric acid to allantoin with enzyme uricase which is deficient in humans and other higher primates [2], and is the main reason why serum UA levels in adult males are...
Long-term exposure to hyperglycemic conditions leads to β-cell dysfunction, particularly mitochondrial dysfunction, and inflammatory and oxidative stress responses, which are considered the primary causes of β-cell death and the hallmarks of diabetes.
Hyperuricemia is largely asymptomatic. The saturation level for uric acid is approximately 6.4 to 6.8mg/dL. The maximum level is about 7.0 mg/dL and symptoms may only become apparent once this level is exceeded significantly. This means that the urates cannot remain dissolved and will begin to...
Interplay between BMI, neutrophil, triglyceride and uric acid: a case-control study and bidirectional multivariate mendelian randomization analysis Haoyuan Lyu Na Fan Jiaxu Chen Nutrition & Metabolism (2025) Nomograms based on ratio indexes to predict severity and prognosis in immune checkpoint inhibit...
(NO); this compound plays a key role in BP regulation as well as maintaining normal function of the blood vessel endothelial layer of cells. It appears that many of the manifestations of MetS can be caused by a fructose-induced rise in uric acid levels[22,24]. A summary of the positive...
(i.e., genes with significant expression changes throughout the acclimatization process). Since genes with similar expression patterns could be involved in the same biological process43,44, we further classified DCGs into different gene clusters based on their expression patterns with thec-means ...
However, it increases the level of uric acid in the body, further resulting in elevated blood pressure. Nitric oxide is the most significant vasodilator. It aids in the maintenance of blood vessel flexibility, and when its levels suppress, the blood pressure rises. Some of the high in sugar...