Objective: To investigate the use of silica hydride-based HPLC columns operating in aqueous normal phase mode to retain and separate uric acid from its metabolites in both reference standard solutions and urine samples. Method: LC-MS instrumentation operating in positive ion mode was used for the ...
Kidney stones.These are little, hard masses — like small stones — that form in your kidneys.One possible cause is too much uric acid. Kidney stones may cause severe pain in your lower back that comes and goes,blood in your urine, throwing up,upset stomach, and an urgent need to pee....
A high uric acid level may occur when your kidneys don't eliminate uric acid efficiently and may result in many health issues.
Uric acid is created in the body due to processing of a chemical compound called Purine, which is naturally present in the body. Purine is also present in certain foods as well. Generally uric acid gets absorbed in the body and excess uric acid is flushed out of the body via urine. Hig...
Click Here For More Info About Uric Acid The study above shows us just how much one can contribute to the likelihood of gout and general inflammatory diseases by weight/diet alone. Extra weight and poor diet habits contribute to major acidity in the body which is a key factor involved in ...
Metformin excreted into urine through active secretion mediated by rOCTs and rMATE1.The aim of this study was to identify the effects of high uric acid on the disposition and its mechanism. In vivo study, hyperuricemic animal model was induced by intraperitoneal injection of potassium oxonate (...
A sensitive, rapid, and specific high pressure liquid chromatographic (HPLC) assay was developed for the determination of salicylic (SA) and salicyluric (SU) acids in plasma and urine. The compounds are extracted into ethyl ether at acid pH, evaporated, and reconstituted prior to instrumental ...
Creatinine clearance, uric acid clearance, 24-hour uric acid urinary excretion, fractional excretion of uric acid, excretion of uric acid per volume of glomerular filtration, urinary uric acid to creatinine ratio, and glomerular uric acid filtered load were calculated using 24-hour urine samples. ...
As the producer of insulin, pancreatic β cells might be affected by elevated serum uric acid levels and contribute to insulin resistance. Previous studies have shown that HUA levels could decrease insulin secretion in β cells, which could contribute to abnormal glucose metabolism (Zhang et al.,...
During a study at 4300 m, urine norepinephrine levels—a marker of sympathetic activity—peaked 4–6 days after altitude exposure (Mazzeo, 1998). The study compared women in different hormonal phases when exposed to high altitude. The urinary norepinephrine levels heart rates both increased over ti...