% saturation and ferritin.And the TIBC, an indirect measure of the iron-carrying protein transferrin, will be lower in the range when all three of the former are too high
Non-transferrin-bound ironIntercellular adhesion molecule-1Iron statusInflammationExcess body iron is associated with increased cardiovascular disease risk, possibly via non-transferrin-bound iron (NTBI)-mediated enhancement of inflammation and oxidation of low-density lipoprotein (LDL).MethodsWe assessed ...
TIBC refers to the maximum amount of iron that can be bound by transferring in 100mL of serum, also known as serum saturated iron. Ferritin can take up and store iron, while transferrin is directly involved in iron transport and metabolism. Zhang et al. (2016) found that the addition of...
Non-invasive brain delivery of neurotherapeutics is challenging due to the blood-brain barrier. The revived interest in transferrin receptor antibodies (TfRMAbs) as brain drug-delivery vectors has revealed the effect of dosing regimen, valency, and affin