While women need some testosterone, high testosterone in women is a concern for a variety of reasons, such as its connection to PCOS, adrenal issues, and other health conditions, as well as its potential to cause symptoms like irregular menstrual cycles, acne, and fertility challenges. For wome...
The effects of androgens on women's bone health are not fully understood. Mendelian randomization (MR) studies using sex-combined data suggest that sex hormone-binding globulin (SHBG) and bioavailable testosterone (BioT) causally affect bone traits. Given significant sex differences in hormone ...
What are signs of high testosterone in females? Symptoms of high testosterone in women include: acne. deep voice. excess hair on the face and body. increased muscle mass. irregular periods. larger-than-normal clitoris. loss of libido.
Interference in direct immunoassay is an important cause of spuriously high testosterone levels in women and serum testosterone measurement by LC-MS is mandatory for optimal clinical interpretation. Although, the exact interferent is not known, DHEA-S has been suggested be partly responsible and furthe...
The implications of high-energy diet and obesity on male infertility have garnered significant attention. Numerous studies have emphasized the pivotal roles of high-energy diet and obesity in male infertility, impacting the male reproductive axis, semen quality, gut microbiota, and testicular microenviro...
Body fat composition and distribution in women with polycystic ovary syndrome Insulin sensitivity was estimated by fasting glucose/insulin ratio and free androgen index (FAI) was calculated as 100 x testosterone/SHBG. Differences ... C Emine,U Kaan,A Lütfi,... 被引量: 0发表: 2011年 Anti-and...
Serum testosterone concentration decreased significantly from 1.8 ± 1.0 to 1.4 ± 0.9 nmol/l (p < 0.01) in 1 KG and the change was greater in 1 KG (30%, p < 0.001) than in 0.5 KG (3%). On the other hand, SHBG increased significantly in 1 KG from 63.4 ± 17.7 to 82.4 ± ...
and steatosis70, whereas de novo fatty acid synthesis induced by sucrose, fructose or glucose has been shown to reduce the hepatocyte-produced sex hormone binding globulin (SHBG)71, which is thought to interact with ERα to regulate the transport of estrogens (and testosterone) into tissues in ...
A critical evaluation of simple methods for the estimation of free testosterone in serum. and non-SHBG-T levels in a large number of sera with SHBG capacities varying from low, as in hirsute women, to extremely high as in hyperthyroidism... A Vermeulen - 《J.clin.endocrinol.metab》 被引量...
PCOS patients showed increased concentrations of total and free testosterone and LH (Table 1) compared with controls, but their obese state or normal weight was not correlated with the levels of those hormones. Sex hormone-binding globulin (SHBG) levels were lower than in the controls in both ...