Nitric oxide (NO) may contribute to the persistence of high-risk human papillomavirus (hrHPV) infection, which has been linked to the development of premalignant lesions and cervical cancer. Our study aimed to examine the relationship between cervical NO metabolite (NOx) levels, hrHPV infection, ...
Oral squamous cell carcinoma in minors is considered to be a distinct entity from OSCC in older patients, with an uncertain etiology. Human papillomavirus (HPV) infection may trigger the initiation and promote the progression of OSCC, but these roles hav
High-risk human papillomavirus (hrHPV)-induced cervical cancer affects more than half a million women every year [1]. Although the oncogenic role of hrHPV is clear in this process, only a minority of hrHPV infections lead to cervical lesions, and ultimately, cancer. Hence, there is a need...
Older women (35–49 years) were significantly more likely to use a condom at last sex compared to their younger counterparts, suggesting that early sex debut is a risk factor to non-condom usage. Having been diagnosed with HIV or having a sexual partner with a known HIV positive status, ...
De novobiosynthesis of kaempferol and quercetin in yeast was improved through increasing the upstream naringenin biosynthesis and debugging the flux-limiting enzymes together with fed-batch fermentations, up to gram per liter level. Our work provides a promising platform for sustainable and scalable prod...
Air pollution is a complex mixture of particles and gases, yet current regulations are based on single toxicant levels failing to consider potential interactive outcomes of co-exposures. We examined transcriptomic changes after inhalation co-exposure to
Last year I needed a solicitor to help sort out my deceased mother’s estate. UK law apparently requires the solicitor to verify identity. With photo ID, to prove you’re the person the identity documents belong to. With no employer’s photo ID and no photo driving licence this could have...
Blood stasis constitution in traditional Chinese medicine (TCM) is believed to render individuals more susceptible to metabolic diseases. However, the biological underpinnings of this constitutional imbalance remain unclear. This study explored the assoc
and malaria health facilities across the country regardless of facility type and managing authority, [9,10,11]. Otherwise, this may lead to an increased risk of coinfection with and treatment failure of other infectious diseases, hence fuelling the epidemic burden of infectious diseases in Ethiopia...
High-grade serous ovarian cancer (HGSOC), which is known for its heterogeneity, high recurrence rate, and metastasis, is often diagnosed after being dispersed in several sites, with about 80% of patients experiencing recurrence. Despite a better understa