Objective Until recently, prenatal screening for trisomy 21 (T21) has been limited to invasive testing or a combination of serum markers and ultrasound. Non-invasive prenatal testing (NIPT) is a sensitive and specific method to identify aneuploidy without the risk of procedure-relat ed loss, but...
Delirium in a patient with trisomy 21 undergoing chemotherapy for high-risk acute lymphoblastic leukemia doi:10.1002/pbc.30176Medical and pediatric oncologyMonica Quirós-MataJoanne DelaneyRuth RussellChristine SabapathyJitka StankovaChani Traube
Overall, 133 trisomies were diagnosed (100 trisomy 21; 18 trisomy 18; 15 trisomy 13). The cell-free DNA screen positive rate was lower in the low-risk vs the high-risk group (0.27% vs 2.2%; P<.0001). The sensitivity and specificity were similar between the groups. The positive ...
However, research shows that the very low false positive rate attributed to cfDNA screening for trisomy 21 does not apply to other conditions. Methods: As a part of the larger study on patient experiences, 40 semistructured telephone interviews were conducted with women who were, or had recently...
Nine hundred and eighty-four (99%) women accepted the offer of an early ultrasound scan at 12-14 weeks' gestation; of these 840(85%) women accepted screening for trisomy 21 (T21) by fetal nuchal translucency thickness (NT) and maternal age (fetal medicine foundation risk assessment programme...
risk of trisomy 21. The average gestational age was 13 weeks and 4 days (+/−1 week and 6 days), average age 33 years and average weight was 70.5 kg. In total there were 13 positive trisomy 21 pregnancies which all were classified correctly using an age adjusted risk cut-off of...
Results: Of the 943 high-risk pregnancies, 550 (58.3%) cases had positive NIPS results, while positive CMA results were detected in 308 (32.7%) cases. The concordance rates between NIPS and CMA were 82.3%, 59.6% and 25.0% for trisomy 21, 18 and 13, respectively. For rare aneuploidies ...
Nine hundred and eighty-four (99%) women accepted the offer of an early ultrasound scan at 12-14 weeks'' gestation; of these 840(85%) women accepted screening for trisomy 21 (T21) by fetal nuchal translucency thickness (NT) and maternal age (fetal medicine foundation risk assessment ...
HDR is usually defined by the number of chromosomes ≥ 50 in the tumor cells. In MM, HDR is characterized by simultaneous trisomy of chromosomes 3, 5, 7, 9, 11, 15, 19, and 21 [24,25]. HDR is a better prognostic marker in patients with NDMM [26]. In patients with HDR, th...
Pregnancy, High-RiskSystematic evaluation of ultrasound findings known to be associated with trisomy 21, at an appropriate gestational age, has been referred... DA Nyberg,VL Souter - 《Seminars in Perinatology》 被引量: 54发表: 2003年 加载更多来源...