High risk definitions used were: 1) preoperative PSA≥20ng/ml, 2) biopsy Gleason score 8-10, 3) clinical stage ≥ T2c, 4) clinical stage T3, 5) D′Amico definition, 6) National Comprehensive Cancer Network definition, and 7) Kattan nomogram 5-year recurrence-free probability of 50% or...
The six high risk definitions were 1) preoperative PSA≥20ng/ml, 2) biopsy Gleason score 8-10, 3) clinical stage≥T2c, 4) clinical stage T3, 5) D'Amico definition, or 6) National Comprehensive Cancer Network definition. Survival was evaluated with the Kaplan-Meier method to generate ...
Sundi D, Wang VM, Pierorazio PM, et al: Very-high-risk localized prostate cancer: definition and outcomes. Prostate Cancer Prostatic Dis 17:57-63, ... Sundi,Wang,M V.,... 被引量: 0发表: 0年 High-dose intensity modulated radiation therapy for prostate cancer: early toxicity and biochem...
High-risk prostate cancer (PCa) harbours a risk of local, regional and systemic relapse requiring the combination of a loco-regional treatment such as external beam radiotherapy for controlling the pelvic-confined disease, combined with an androgen deprivation therapy (ADT) to potentiate irradiation ...
Patients with high-risk prostate cancer treated with curative intent are at an increased risk of biochemical recurrence, metastatic progression and cancer-related death compared with patients treated for low-risk or intermediate-risk disease. Thus, these
Prostate cancer is a common type of cancer that affects men, and it occurs in the prostate gland which is a part of the male reproductive system. High-risk prostate cancer refers to aggressive and advanced forms of the disease that are more likely to spread to other parts of the body. T...
Management of high-risk localized prostate cancer: the integration of local and systemic therapy approaches Using a combination of PSA, Gleason score, and clinical stage, it is possible to identify a group of patients with prostate cancer who have a high risk of ... PIM Thompson - 《Urologic...
The definition of high-risk localized and locally advanced prostate cancer varies between guidelines and inclusion criteria for key clinical trials such as the STAMPEDE study [1]. For the APCCC 2017 St Gallen meeting, the European Association of Urology (EAU) guideline definition was used (high-...
Response:Our study provides evidence to suggest that delivering adjuvant as compared to early salvage radiation therapy can reduce the risk of death by decreasing death from prostate cancer in men found to have adverse pathology at surgery.
The combination of histologic grade and proliferative activity allows the stratification of patients into low and high risk groups. Cancer 1997; 79:1956-63. © 1997 American Cancer Society. Carcinoma of the prostate is a heterogeneous disease with different biologic activity and highly unpredict...