Extended thromboprophylaxis with low-molecular-weight heparins after hospital discharge in high-risk surgical and medical patients: A review - ScienceDirect Background: Prophylaxis against venous thromboembolism (VTE) is routinely administered during the hospital stay in at-risk surgical and medical patient...
At present, the characteristics of double-hit multiple myeloma (DHMM) are unknown. We retrospectively analyzed the clinical data from 433 new diagnosed MM patients and found that DHMM have a higher β2-MG level and percentage of bone marrow plasma cell.
Other differences pertain to the trial design (open-label vs double-blind), the study population (all comers vs patients with high risk), modes of bleeding ascertainment (site-reported vs adjudicated), and protocol adherence.2 The results from TWILIGHT are consistent with pharmacodynamic effects of...
The purpose of this study was to compare the effects of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) on weight, body composition, blood lipid indicators, and metabolic status in college students living with ob
Kaplan-Meier estimates of the incidence of death from any cause, nonfatal myocardial infarction, or nonfatal stroke 1 year after randomization (per-protocol population). The per-protocol population included patients who underwent randomization and had no major deviations from the protocol. The HR sho...
In this work, we aimed to elucidate iASPP expression patterns in defined AML patient cohorts and investigate the functional consequences thereof. Prognostic value of iASSP and consistency with current AML risk models were determined and validated in independent patient sets. An iASPP-interference model...
9 Briefly, heparin-anticoagulated blood was layered over a discontinuous percoll gradient (Seromed) consisting of two layers of 68% and 63% percoll, respectively. After centrifugation, PMN were harvested from the percoll interphase and the remaining erythrocytes were removed by hypotonic lysis. ...
Previous studies have indicated that CTX, an alkylating agent, is widely used as an antitumor and immunosuppressive drug and is associated with the highest risk of POF [20, 21]. Chemotherapy-induced follicular and stromal cell senescence and apoptosis can lead to decreased ovarian weight, structural...
or hypercoagulable state but were felt to be at high risk for the use of heparin.MethodsEight patients in our neurocritical care unit required anticoagulation but were felt to be poor candidates for heparin either due to heparin-induced thrombocytopenia or due to high risk for intracranial hemorrh...
Mitophagy, a prominent cellular homeostasis process, has been implicated in modulating endothelial cell function. Emerging evidence suggests that extracellular vesicles (EVs) participate in intercellular communication, which could modulate tumor angiogen