Background The Ontario Breast Screening Program was expanded in 2011 to offer annual MRI and mammography to women with high‐risk genetic mutations (e.g., BRCA1/2) and women with strong family histories and ≥25
Advances in counseling and surveillance of patients at risk for pancreatic cancer. Gut 2007;56:1460–1469 Article PubMed Google Scholar Eppel A, Cotterchio M, Gallinger S. Allergies are associated with reduced pancreas cancer risk: A population-based case–control study in Ontario, Canada. Int...
In conclusion, we performed a GWAS of WM/LPL and identified two independent loci that are associated with the risk of WM/LPL with substantially higher than expected estimated odds ratios for a GWAS of an adult cancer. It is remarkable that the effect size for 6p25.3 is substantively different...
Methylation is a common epigenetic modification which may play a crucial role in cancer development. To investigate the association between methylation of COX-2 in blood leukocyte DNA and risk of gastric cancer (GC), a nested case–control study was conducted in Linqu County, Shandong Province, ...
High-risk large B-cell lymphoma (LBCL) has poor outcomes with standard first-line chemoimmunotherapy. In the phase 2, multicenter, single-arm ZUMA-12 study (ClinicalTrials.gov NCT03761056) we evaluated axicabtagene ciloleucel (axi-cel), an autologous
With these terms in the model, none of the other predictors that had survived the domain-wise screening procedure (Table 3) were related to conversion risk, indicating that their predictive associations were redundant with the other model terms. In particular, treatment with antipsychotic drugs ...
selectively identified breast carcinomas with elevated cardiotoxicity risk60, locoregionally advanced non-small cell lung cancer (NSCLC)61,62, and high-risk head and neck malignancies63. It is worth questioning if there is a technique that is as accurate as hadronic beams, as easily clinically dep...
Aetna considers low-level laser therapy medically necessary for prevention of oral mucositis in persons undergoing cancer treatment associated with increased risk of oral mucositis, including chemotherapy and/or radiotherapy, and/or hematopoietic stem cell transplantation. Experimental, Investigational, or Unpr...
(ie. CKFBs/CKRs), and if certain CK forms are not separated in chromatography space, there is a risk of biased quantification through a phenomenon known as mass spectrometer inter-channel ‘cross-talk’. Inter-channel cross-talk occurs when subsequent multiple reaction monitoring (MRM) ...
Chiarelli and her colleagues followed 2,207 women, aged 30 to 69, all at high risk of breast cancer, to determine the effect of the two screenings. The women were enrolled in the Ontario Breast Screening Program, which expanded in July 2011 to screen high-risk women in a special program...