High-resolution mass spectrometry (HRMS) using double- focusing mass analyzers was established in chemistry labora- tories in the 1960s. Coupled to a direct insertion probe or to gas chromatography, it revolutionized the elemental analysis of organic compounds. It also became a powerful tool in bio...
of-flight(TOF)high-resolutionmassspectrometry(HRMS).Therepresentativenessofthoseresultsfortheentiresamples hasbeencheckedusing 13 CNMRspectroscopy.Lastly,Kendrickmassdefectanalysishasbeenproposedasan alternativeanduser-friendlydatatreatmentmethod. RESULTS:TheshortestchainsisolatedbySECfractionationandmass-analyzedbyHRMS...
Mass spectrometry imaging (MSI) is a technology that enables the visualization of the spatial distribution of hundreds to thousands of metabolites in the s
High resolution mass spectrometry 来自 Springer 喜欢 0 阅读量: 30 作者: R Kondrat 摘要: A general solution for data processing of large numbers of micrometer- or submicrometer-particle mass spectra in aerosol analysis is described. The method is based on immediate evaluation of bipolar laser ...
High-resolution mass spectrometrydoi:10.1016/b978-0-12-819967-1.00016-5M. A. G. WallaceJames P. McCordBreathborne Biomarkers and the Human Volatilome
‘Rowe Red’ was used to study the chemical constituents of the epidermal cell layer using matrix-free laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometric imaging (LDI-FT-ICR-MSI). The high resolution of this technique allowed phenylphenalenone-type compounds to ...
Mass spectrometry-based qualitative and quantitative (bio)molecular analysis is a corner stone in the state-of-the-art pipelines in systems biology and environmental sciences. High-resolution and efficient tandem mass spectrometry methods and techniques are the essential analytical capabilities for the in...
high-resolution mass spectrometry and automated analysis of the resulting mass spectra for the identification of cross-linked peptides, cross-linking sites and the cross-linked RNA oligonucleotide moieties of such RNA-binding proteins. The workflow can be applied to any RNA-protein complex of interest...
Ultra-high-performance liquid chromatography high-resolution mass spectrometry (UHPLC–HRMS) variants currently represent the best tools to tackle the challenges of complexity and lack of comprehensive coverage of the metabolome. UHPLC offers flexible and efficient separation coupled with high-sensitivity ...
The application of the Burg algorithm for maximum entropy spectral analysis to the time domain signals obtained in a Fourier transform mass spectrometer (FTMS) has been further explored with particular attention to its high-resolution capabilities and with the purpose of exploring the effect of the ...