High resolution mass spectrometry imagingAP-SMALDI imagingThe pomace fly or fruit fly Drosophila melanogaster is known as a cost-effective model organism widely used to study neurological diseases and metabolite-related diseases. Among these metabolites, lipids play important roles in energy homeostasis, ...
Raster scanning the samples through the laser focus enables the acquisition of mass spectrometry data which can be processed into images with pixel size 10 m without oversampling, corresponding to cellular level resolution.Proceedings of SPIERonan A. BattleDaniel SimonYuchen XiangKenneth RobinsonTimothy...
‘Rowe Red’ was used to study the chemical constituents of the epidermal cell layer using matrix-free laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometric imaging (LDI-FT-ICR-MSI). The high resolution of this technique allowed phenylphenalenone-type compounds to ...
Mass spectrometry imaging () is widely used for clinical research because when combined with histopathological analysis the molecular signatures of specific /regions can be extracted from the often-complex histologies of pathological tissues. The ability of to stratify patients according to disease, progn...
摘要: High-spatial resolution mass spectrometry imaging (MSI) is crucial for the mapping of chemical distributions at the cellular and subcellular level. In this work, we improved our previous laser optical关键词:Mass spectrometry imaging MALDI Laser spot size Resolution Maize Root Optics ...
High spatial resolution imaging mass spectrometry and classical histology on a single tissue section . J Mass Spectrom 2011; 46 :568–571Deutskens F, Yang J, Caprioli RM (2011) High spatial resolution imaging mass spectrometry and classical histology on a single tissue section. J Mass Spectrom ...
Mass spectrometry imaging (MSI) is a technology that enables the visualization of the spatial distribution of hundreds to thousands of metabolites in the same tissue section simultaneously. Roots are below-ground plant organs that anchor plants to the soil, take up water and nutrients, and sense ...
Spatial proteomics has the potential to significantly advance our understanding of biology, physiology and medicine. Matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI) is a powerful tool in the spatial proteomics field, ena
Development and Application of a High-Resolution Imaging Mass Spectrometer for the Study of Plant Tissues. Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) or imaging mass spectrometry (imaging MS) has been a powerful tool to m... Katsutoshi,Takahashi,Toshiaki,.....
Herein, we describe a protocol for robust imaging of tissue sections with a high (better than 10-μm) spatial resolution using nanospray desorption electrospray ionization (nano-DESI) mass spectrometry, an ambient ionization technique that does not require sample pretreatment before analysis. In this...