The FDA has issued a de novo clearance for a minimally invasive high-intensity focused ultrasound (HIFU) device called Sonablate 450 for prostate tissue ablation. The device is intended for patients with low- to high-risk prostate cancer with a PSA lower than 10 ng/mL who have progres...
Biochemical recurrence status (BCR, defined as PSA > 0.2 ng/mL), surgical margin status, and pre-surgery serum PSA levels (PSA < 10 ng/mL = low, PSA ≥ 10 ng/mL = high) were not statistically different between the two groups (Fisher’s exact test, P...
chips and nadir PSA on univariate analysis. However, the only significant predictor for HIFU failure was the nadir PSA value by multivariate Cox regression analysis. The operation-related complications were minimal. Although both the period and number of patients were limited to evaluate the clinical ...
Materials and methods Patients with initial or locally advanced, biopsy proven prostate adenocarcinoma, Gleason scored and considered of unfavorable outcome, with a life expectancy of at least 5 years, pre- treatment PSA levels <50 ng/ml and prostate volume up to 60 cc, after signing an ...
The respective preoperative prostate-specific antigen (PSA) level was 10.4ng/mL, and the operative time was 45 (range, 30–90) min. The total applied laser energy ranged 60–120 (mean, 90±25) kJ. The maximal urinary flow rate after surgery 14mL/s, and the postvoided residual urine ...
If a new user pays attention to this topics, if he/she has experience in transrectal ultrasound, TURP, pelvic anatomy and computer handling, he/she should be able to integrate transrectal HIFU into his/her armentarium after approximately 15 treatments....
Moreover, MMPs and other proteases (such as prostate-specific antigen – PSA) are involved in semen liquefaction4, in the female reproductive tract. Semen liquefaction is a necessary step for further sperm processes related to fertilization, such as capacitation5. MMPs have also been shown to ...
Potential covariates including age, body mass index (BMI), prostate volume (PV) and serumprostate-specific antigen (PSA) were defined and further subgroup analyses were utilized. The HPS group had a significantly higher education level, annual household income and larger prostate size. Compared with...
The time to BCR was defined as the interval between the date of the RP and the date of a prostate-specific antigen (PSA) level above 0.2 ng/mL and rising, or when a decision to proceed with additional therapy was made. Bone metastasis onset and death from PC defined the metastasis-free...
Therefore, no patients died due to surgery-related reasons. Regarding functional results, the present series confirmed that ThuVEP provided immediate LUTS relief, together with significant QoL and Qmax improvements that persisted for 12 months after surgery. The one-year median PSA decreased by 70.4%...