Protein ingestion acutely elevates amino acid levels in blood and atherosclerotic plaques, stimulating macrophage mammalian target of rapamycin (mTOR) signalling. This is causal in plaque progression, because the effects of dietary protein are abrogated in macrophage-specific Raptor-null mice. ...
Hemoglobin is a protein in red blood cells and hematocrit is a measurement of the amount of red blood cells as related to total blood cell count. Both hemoglobin and hematocrit are used to diagnose anemia. Both hemoglobin and hematocrit can be measured from standard blood tests, and both value...
(microtubule associated protein 2, a well-known molecular marker for dendrite formation) andCALCA(calcitonin gene-related peptide, also abbreviated as CGRP, a major neuromodulator in sensory nerves21). Moreover, functional enrichment of up/downregulated genes between sham-operated and post-PRATA SHRs...
Keep reading to learn about protein’s role in your health, how to determine if a food is a complete protein, and what sources of food and supplements are the best for continued good health. Our guide shares with you the benefits of eating a diet high in protein, including how protein h...
Hypertension (HTN) or high blood pressure, sometimes arterial hypertension, is a chronic medical condition in which the blood pressure in the arteries is elevated. This requires the heart to work harder than normal to circulate blood through the blood vessels. Blood pressure involves two ...
(enzymes that damage the cell wall of bacteria) and work by digesting engulfed cell particles. An enzyme is a type of protein that helps produce chemical reactions in the body. When a granulocyte is released in the blood, it stays there for about four to twelve hours and then travels to ...
Short-term effects of protein intake, blood pressure, and antihypertensive therapy on glomerular filtration rate in the Modification of Diet in Renal Disease Study. J Am Soc Nephrol. 1996;72097- 2109Google Scholar 34. van de Ven PJBeutler JJKaatee RBeek FJMali WPKoomans HA Angiotensin ...
For KGN cells exposed to insulin, IPA identified a cell proliferation-related factor, the yes associated protein 1 (YAP1), as a significant and activated (z-score = 2,438, p-value = 3,71E-02) upstream regulator; while a chemoattractant for macrophages, the colony-stimulating factor 1 (CS...
In this study, we extended co-indexing of transcriptomes and epitopes (CITE) to the spatial dimension and demonstrated high-plex protein and whole transcriptome co-mapping. We profiled 189 proteins and whole transcriptome in multiple mouse tissue types w
Cellular models are needed to study human development and disease in vitro, and to screen drugs for toxicity and efficacy. Current approaches are limited in the engineering of functional tissue models with requisite cell densities and heterogeneity to ap