High potassium promotes mutual interaction between (pro)renin receptor and the local renin-angiotensin-aldosterone system in rat inner medullary collecting duct cells. Am J Physiol Cell Physiol. 2016;311:C686–95. https://doi.org/10.1152/ajpcell.00128.2016. Article PubMed PubMed Central Google ...
Fig. 3 A KCNE1 functional assay using a gain-of-function KCNQ1 variant.AVoltage clamp measurements of outward potassium currents in HEK293T cells transfected with various combinations of WT or S140G KCNQ1 and/or KCNE1-HA. At the resting potential of HEK293T cells (~ −25 mV, dotted...
Fig. 3 A KCNE1 functional assay using a gain-of-function KCNQ1 variant.AVoltage clamp measurements of outward potassium currents in HEK293T cells transfected with various combinations of WT or S140G KCNQ1 and/or KCNE1-HA. At the resting potential of HEK293T cells (~ −25 mV, dotted...
Aim of the study: To detect the difference between acetate and bicarbonate dialysis as regard to the type and frequency of arrhythmia in those patients. Study design: This study was done on 20 male patients age 51–73, all have history of heart disease. Patients were divided into 2 equal ...
A weight change of >2 kg, a resting heart rate <50 beats/min or >80 beats/min, new-onset sustained arrhythmia, or a systolic blood pressure <90 mm Hg or >140 mm Hg were considered an indication for close review of the patient’s management. During titration of beta-blockers, a ...
hERG potassium channels and cardiac arrhythmia. hERG potassium channels are essential for normal electrical activity in the heart. Inherited mutations in the HERG gene cause long QT syndrome, a disorder ... MC Sanguinetti,Tristani Firouzi M - 《Nature》 被引量: 1759发表: 2006年 Intracellular K+...
Most studies suggested an association between lower potassium levels and a higher risk of atrial fibrillation [68,69,70,71]. However, our results reported atrial fibrillation as the most common arrhythmia observed among hyperkalemic patients. This finding is concordant with Varga et al.’s findings...
MicroRNAs (miRNAs) participate in atrial remodeling and atrial fibrillation (AF) promotion. We determined the circulating miRNA profile in patients with AF and heart failure with reduced ejection fraction (HFrEF), and its potential role in promoting the arrhythmia. In plasma of 98 patients with HFr...
to treat hypertension. They block the effects of the sympathetic nervous system on the heart. This reduces the workload of the heart by requiring less blood and oxygen, which slows the heart rate. They can be used to treat other conditions as well, including abnormal heart rate (arrhythmia)...
to treat hypertension. They block the effects of the sympathetic nervous system on the heart. This reduces the workload of the heart by requiring less blood and oxygen, which slows the heart rate. They can be used to treat other conditions as well, including abnormal heart rate (arrhythmia)...