An increased maintenance dose of clopidogrel (150 mg) or a more potent thienopyridine such as prasugrel can reduce the mean platelet response in populations of patients (4-9). Clinical data support the hypothesis that this strategy can potentially improve the population-wide efficacy of P2Y_12 ...
could indicate infection or inflammation. High levels of red blood cells, which carry oxygen and carbon dioxide through your dog's body, could occur due to issues like dehydration or bone marrow disease. A low platelet count could be a sign of immune mediated disease. ...
High residual platelet reactivity on standard clopidogrel maintenance dose predicts increased responsiveness to the double-standard dose in an assay-dependent manner.Despite the documented benefit of dual antiplatelet therapy with aspirin and clopi-dogrel in large populations, adverse cardiovascular events ...
Furthermore, in vascular smooth muscle cells, HCy decreased SAM and increased SAH; the consequent decrease in the ratio of SAM/SAH led to promoter hypomethylation of the platelet-derived growth factor (PDGF) gene [43]. These findings provided a novel insight into the molecular association between...
Dog, pig, and rat kidneys contain a similar enzyme and the properties of the purified canine kidney enzyme are similar to those reported for type IV phosphodiesterase (PDE) for lung and skeletal muscle. In contrast to these tissues, liver, heart, and platelet enzymes demonstrate cGMP inhibition...
Milk residues and performance were evaluated in lactating cows that were fed up to 10 times the recommended dose of monensin. Following an acclimatization period of 14 d, during which cows were fed a standard lactating cow total mixed ration containing 24 ppm monensin, 18 lactating Holstein dairy...
4.Can be used as choleretic drug for uncomplicated chronic cholecystitis, cholangitis in patients with bile discharge barriers. It can also speed up the process of blood clotting and increase blood levels of thrombin yuan, increased platelet count, they can ...
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Mclcan found it from the liver tissue of dog in the study of the clotting mechanism. Brinkous et al proved that heparin having anticoagulant activity. After the first application of heparin as an anticoagulant in clinical filed, it has drawn worldwide attention....