High-mobility group box 1 (HMGB1) protein:friend and foe[J].Cytokine & Growth Factor Reviews,2006,(3):189-201.doi:10.1016/j.cytogfr.2006.01.003.Ulloa L and Messmer D. High-mobility group box 1 (HMGB1) protein: friend and foe. 520 Cytokine Growth Factor Rev 17: 189-201, 2006....
High-mobility group box 1 protein (HMGB1), which previously was thought to function only as a nuclear factor that enhances transcription, was recently discovered to be a crucial cytokine that mediates the response to infection, injury and inflammation. These observations have led to the emergence ...
高迁移率族蛋白B1(high mobility group box 1 protein, HMGB 1)是巨噬细胞释放出一种核蛋白。HMGB家族有3个成员,即HMGB1、HMGB2和HMGB3,三者在氨基酸序列上有80%的一致性。HMGB1是含量最丰富的HMG蛋白,在典型的哺乳动物细胞内约有106个分子,平均10~15个核小体即可含有1个HMGB1分子。HMGB1广泛分布于淋巴组织、...
High-mobility group box 1 (HMGB1) is a ubiquitous protein that regulates transcription in the nucleus, and is an endogenous damage-associated molecular pattern molecule that activates the innate immune system. HMGB1 activates the TLR4 and RAGE recepto, inducing downstream signals reminiscent of cytokin...
The aim of this prospective study was therefore to evaluate the diagnostic value of preoperative serum High Mobility Group Box Protein-1 (HMGB-1) levels in patients with Acute Appendicitis (AA) who show normal white blood cell count (WBC) counts. Our study was carried out from October 2010...
The nuclear protein high-mobility group box 1 (HMGB1) can be passively released by necrotic cells or secreted actively by several cell types to regulate immune and inflammatory responses, as well as tissue remodeling. We herein aimed to characterize the effect of insulin resistance on HMGB1 in ...
中文名称:Recombinant Human High-Mobility Group Box 1英文名称:Recombinant Human High-Mobility Group Box 1 产品类别:重组蛋白 中文名称 【HMGB1】重组人高迁移率族蛋白框1 英文名字 Recombinant Human High-Mobility Group Box 1 供应商 ProSpec 产品货号 ...
该HMGB1(高迁移率族蛋白1),人|HMGB1 (High mobility group box 1), Human产品的溶解建议详情,参考产品说明书。 保存建议 冻干蛋白应在-20 ℃下储存 其他 Croyez Bioscience专为科学家提供蛋白质研究领域所有应用解决方案产品。提供GMP和RUO级重组蛋白,mRNA合成原料,分子诊断原料,过敏原原料,COVID -19抗体和抗原及...
产品详情 Name:Recombinant HMGB1 (High mobility group box 1), Human, AF; Source:Human Cytokines; UniProt ID:P09429; Host:Escherichia coli; Reactivity:Measure by its ability to induce TNF alpha in RAW264.7 cells. The ED50 for this effect is <10 μg/mL.; Application:Cell culture, Elisa; ...
高迁移率族蛋白B1(high mobility group protein,HMGB1)是一种高度保守的核蛋白,广泛分布于哺乳动物细胞.随着其晚期促炎作用的发现,HMGB1成为近年来危重医学研究的热点之一.本文就其家族分类、基因和蛋白结构、细胞生物学效应方究进展进行综述. 应用类型 ELISA, Western blot and immunohistochemistry ...