SNP markers of high blood pressure, high blood pressure risk determination method, and how to use the hypertension susceptibility gene-deficient small animalsPROBLEM TO BE SOLVED: To provide a gene marker comprising SNP useful for identifying a hypertension development risk and a method for ...
The relationship between obesity markers and blood pressure was not observed in males aged between 14–17 years. Puberty had been associated with a reduction in adipose tissue, especially in males. It is known that adipose tissue is responsible for releasing a number of cytokines, including leptin...
Objective To update its 2013 recommendation, the USPSTF commissioned a review of the evidence on the benefits and harms of screening, test accuracy, the effectiveness and harms of treatment, and the association between hypertension and markers of cardiovascular disease in childhood and adulthood. Popula...
To confirm whether differentiation of splenic F4/80lowmonocytes into F4/80highmacrophages could be reproducible similar to circulating blood F4/80lowmonocytes in the liver, splenic F4/80lowmonocytes were co-cultured with LSECs of D2 clodronate-treated mouse liver. Flow cytometry analysis revealed tha...
appreciable number in unstressed hearts (Figure 2Eand2F;Figure VI in the Data Supplement) increased dramatically in hearts of mice treated with AngII and expressed high levels of periostin (Figure 2E). We refer to these cell populations as Fibroblast-Cilpand Fibroblast-Thbs4, reflecting markers ...
Variations in oral microbiota were associated with inflammatory markers in IBD Figure 5 (Fig. 5A - 5C). The levels of WBC, CRP, FC, and ESR were significantly higher in IBD patients than in HCs (Supplementary Fig. S4A - D). At the phylum level, the relative abundances of Tenericutes ...
1A). Sixteen clusters were identified based on the expression of differentially expressed genes (DEGs) in each cluster and known markers (Fig. 1B, Additional file 1: Fig. S2A and Additional file 2: Table S1), which were grouped into 3 main subtypes: mesenchymal stem cells (MSCs), multi...
The latter included hevin, thrombospondin-1, and mac25/IGFBP-rP1, which is a secreted growth factor-binding protein previously found to accumulate specifically in tumor blood vessels. Biochemical and histochemical analysis confirmed the identification of mac25 and DARC as novel markers of the HEVECs...
To determine the relationship between activation status of DCs and their IL-12 production in homeostasis, we assayed expression levels of various activation markers of DC1 together with their IL-12 production. To do so we measured IL-12B p40 because DC1 are essentially all IL-12A p35+ while ...
blood cell DNA covering a large genomic region (508 genes; 2 megabases; >60,000× raw depth) in a prospective study of 124 patients with metastatic cancer, with contemporaneous matched tumor tissue biopsies, and 47 controls without cancer. The assay displayed high sensitivity and specificity,...