PHOSPHONIC ACID DERIVATIVE AND THERAPEUTIC AGENT FOR DISEASE IN WHICH HIGH PHOSPHATE LEVEL IN BLOOD PARTICIPATESThe present invention relates to a series of activity that new phosphonate derivatives have anti-hyperphosphatemia. (I) in formula: one kind is between (CH2)-N- ,-CO- ,-(CH2) n-CO...
Effect of radon exposure on superoxide dismutase (SOD) activity in rats Effect of radon exposure on the activities of superoxide dismutase (SOD) in blood, kidney, liver and spleen of male Wistar rats were investigated. Radon ex... MA, JIZENG,YONEHARA, HIDENORI,IKEBUCHI, MAKOTO,... - 《Jo...
The homing of the cells led to effective engraftment and faster regeneration of the critical blood lineages, which elicited 100% survival of the mice receiving lethal doses of radiation. The Human Long-Term Culture Initiating Cells (LTC-ICs), Severe Combined Immunodeficient (SCID) - Repopulating ...
Hypertension is a pathological condition of persistent high blood pressure (BP) of which the underlying neural mechanisms remain obscure. Here, we show that the afferent nerves in perirenal adipose tissue (PRAT) contribute to maintain pathological high B
Analyses were performed on citrated whole blood diluted 1:4 in phosphate-buffered saline incubated with either PAC1 fluorescein isothiocyanate-conjugated monoclonal antibody (Becton Dickinson), anti-P-selectin phycoerythrin-conjugated monoclonal antibody (Becton Dickinson), or anti-fibrinogen fluorescein ...
The ATP concentration was then standardized to the quantity of protein in the supernatant as assessed with a Bicinchoninic Acid Protein Assay Kit (Sigma, St Louis, Mo). Data were normalized to total protein, and the cellular ATP level was expressed in nanomoles per microgram of protein. ...
(IL)-37isanovelmemberoftheIL-1cytokinefamily.However,asaresultoflackingefficient methodtogeneraterelativelylargequantityofIL-37,littleisknownofitsfunctionsinman.Inthepresent study,therecombinanthumanIL-37bcontainingaC-hexahistidinetagwasexpressedinEscherichiacoli (E.coli).TheexpressionlevelofIL-37binE.coli...
The physiologic oxygen tension (physioxia) within tissues in the human body is well below the atmospheric level (hyperoxia), with the highest level in the alveoli (110 mmHg) and arterial blood (100 mmHg) [3]. Articular chondrocytes live in a physiologic environment of 1–5 % (8–40 mmHg...
Subsequently, this team found that elevated serum IgG4 level was associated with chronic antibiotic-refractory pouchitis among patients with IBD17. Rebours et al.18 compared the infiltration of mucosal IgG4+ plasma cells in intestinal tissues of patients with IBD and patients with autoimmune ...
(Fig.6i). Fractions of total CD11b+cells, Ly6Chiinflammatory monocytes and Ly6Ghineutrophils were significantly increased in blood in comparison to tumor-free mice (Fig.6j), and this correlated with the increase of these cell subsets in the lung. In comparison to MDA-MB-231, Ly6G+cells ...