Celiac DiseaseIntestinal NeoplasmsDuodenal NeoplasmsImmunoglobulin ABiopsyAutopsyLymphoma, Non-HodgkinA case of a 55-year-old woman with malabsorption and high serum IgA level is described. On peroral jejunal biopsy the diagnosis of adult celiac disease was considered. Malabsorption temporarily improved on...
The histo-blood group Lewis antigens are found in most human epithelial tissues, as far as they are terminal parts of glycolipids and glycoproteins. There are two types of Lewis glycans: (A) Lea, sLea and Leb, all derived from type 1 structures (Galβ1- 3GlcNAc, Lec) and their ...
How the Test is Done Doctors often measure IgA, IgG, and IgM together to get a snapshot of your immune function. A lab tech will usually take a sample of your blood by inserting a needle into a vein in your arm. The blood collects in a tube or vial. Another way to do this test ...
We found that asymptomatic persons with celiac disease may have IgA-EmA. We found a 100% specificity of IgA-EmA in the tested population of blood donors, whereas the sensitivity was about the same as that of IgA-AGA. This result of a + PV of 100% indicates that a positive IgA-EmA ...
Because of the different sensitivity and specificity of serologic tests, the search for silent celiac disease is usually performed with the combined or sequential use of several tests. Among these, the IgA-class endomysium antibody test has the highest specificity and positive predictive value, but...
ofthe assay was estimated to be 100% (151/151). By application of the Bayes theorem in a population with no or few symptoms, the -i- PV for celiac dis- ease was therefore 100% for IgA-EmA, both as a single test and in serial testing together with igA- AGA.GrodzinskyHed...
1993. Down's syndrome and celiac disease: The prevalence of high IgA-antigliadin anti- bodies and HLA-DR and DQ antigens in trisomy 21. J Pediatr Gastroenterol Nutr 16:265-268.Castro M, Crino A, Papadatou B, et al. Down's syndrome and celiac disease: the prevalence of high IgA-anti...
Methods: Sera from 2000 healthy blood donors were screened for IgG AGA and IgA AGA with an enzyme-linked immunosorbent assay test. All those with increased AGA levels, those with intermediate levels, and random samples with low levels were tested for AEA, using both monkey esophagus (ME) and...