High-grade tumors of the brainstem in adults and children, excluding diffuse intrinsic pontine glioma (DIPG), are rare. In adults, these tumors are almost exclusively malignant gliomas, while in children approximately 60% are high-grade gliomas and 40% are embryonal tumors. In almost all cases,...
The treatment of high-grade brain tumors involves surgical resection followed by targeted fractionated radiation therapy with concomitant chemotherapy and then follow-up chemotherapy. Conventional proton magnetic resonance (MR) imaging plays a role in the initial detection and anatomical and physiological ...
high‐grade neuroepithelial tumorCentral nervous system high‐grade neuroepithelial tumors with BCOR alteration (CNS HGNET‐BCOR) are a recently reported rare entity, identified as a small fraction of tumors previously institutionally diagnosed as so‐called CNS primitive neuroectodermal tumors. Their ...
Fig. 2: CAR-T cell therapies in brain tumors and their limitations. a and b CAR-T cell therapy targeting brain tumors face multiple challenges, including tumor heterogeneity, antigen loss, immunosuppressive tumor microenvironment, blood–brain barrier, limited trafficking, and CAR-T cell-associated ...
Oncogenes encode proteins that promote tumor growth, survival under adverse conditions, and invasion. Many studies have detected amplified oncogenes in high grade brain tumors, especially glioblastoma or glioblastoma multiforme (GBM). Therefore, assays to identify amplified genes are proposed to become ...
网络释义 1. 高分级脑胶质瘤 高分级脑胶质瘤,High-grade... ... )High-grade gliomas高分级脑胶质瘤) polymer 高分子 ... www.dictall.com|基于 1 个网页 2. 高度惡性之神经胶质瘤 属於高度惡性之神经胶质瘤(high-grade gliomas),一般說來,高惡性度之肿瘤细胞的生 ...
High-grade gliomas (HGGs) constitute approximately 10 % of all childhood brain tumors and include AA (anaplastic astrocytoma), anaplastic oligodendroglioma (AO), and glioblastoma (GBM). Clinical symptomatology varies greatly with age and can be nonspecific, especially in younger children. Conventional ...
tumor treating fields high-grade glioma mitotic spindle formation brain tumor temozolomide standard therapy 1. Introduction Gliomas originate from glial cells and are the most common intracranial tumor. According to the World Health Organization (WHO), grade III and grade IV gliomas belong to high-gra...
The relationship between diffusion heterogeneity and microstructural changes in high-grade gliomas using Monte Carlo simulations KurtosisDiffusivityHeterogeneityGliomasPEDIATRIC BRAIN-TUMORSATTENUATED MR SIGNALDiffusion-weighted imaging (DWI) may aid accurate tumor grading. Decreased diffusivity... CY Lee,KM Benne...
Dynamic CT perfusion imaging of intra-axial brain tumours: differentiation of high-grade gliomas from primary CNS lymphomas. Eur Radiol 2010;20:2482-90Dynamic CT perfusion imaging of intra-axial brain tumours: differentiation of high-grade gliomas from primary CNS lymphomas[J] . Peter Schramm,...