The designation high-grade B-cell lymphoma traditionally has been used as a general term for B-cell lymphomas that are morphologically aggressive with many mitotic figures, often a starry-sky pattern, and a high proliferation rate as shown by Ki-67 expression. These morphological features correlate...
(2-y overall survival rate of 41% in SHL vs. 48% in DHL; P=0.35) and significantly worse than patients with diffuse large B-cell lymphoma and B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma, without MYC and BCL2 ...
High‐grade T‐cell lymphoma complicating B‐cell chronic lymphocytic leukemia: An unusual manifestation of “Richter's syndrome” Chronic lymphocytic leukemiaInfusion related adverse events (AE) with day 1 rituximab in patients with B-cell non-Hodgkin''s lymphoma (NHL) are common... N Alex,EL ...
Herein, we present an elderly patient with a diagnosis of high-grade B-cell lymphoma, in whom a complete response was observed after prolonged COVID-19 infection. Case summary An 81-year-old female patient received her first cycle of R-CHOP (rituximab, cyclophosphamide, vincristine, and ...
Additionally, patients with high-grade B-cell lymphoma (HGBL) characterized by gene rearrangements ofMYCandBCL2and/orBCL6(that is, double- or triple-hit lymphomas) have a poor prognosis with standard first R-CHOP, with CRR <50% (refs.10,11,12). These high-risk patients are also more li...
High-grade B-cell lymphoma of the peritoneum as a result of transformation of a CD5-negative monoclonal B lymphocytosis population in a patient with myelodysplastic syndrome treated with 5-azacytidineHigh-grade B-cell lymphoma of the peritoneum as a result of transformation of a CD5-negative monoc...
Diffuse large B-cell lymphomas with aberrations in MYC, BCL2 and/or BCL6 by genetic alterations or protein expression represent a group of high grade B-cell lymphomas with inferior outcomes when treated with standard RCHOP chemotherapy. As a result, intensified induction regimens have been suggeste...
摘要: Comments on an article in 'Gut' about low and high-grade mucosa associated lymphoid tissue (MALT) lymphomas. Causes of confusion over the terminology; MALT classification from the World Health Organization.关键词: mucosa associated lymphoid tissue gastric lymphoma classification ...
Polatuzumab vedotin has been approved in combination with rituximab, cyclophosphamide, doxorubicin, and prednisone for previously untreated diffuse large B-cell lymphoma.
High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology Author links open overlay panelDavid W. Scott 1, 2, Rebecca L. King 3, Annette M. Staiger 4, 5, Susana Ben-Neriah 1, Aixiang Jiang 6, Heike Horn 5, Anja Mottok ...