3A and Supplementary Fig. 1D). These effects were also evident with the selective ERα ligand PPT (Fig. 3A). Thus, our experimental set-up confirms that exogenous E2 via ERα impacts obesity, fasting glucose, total fat and VAT ratios in males....
1.5H coverslips at a density of 30,000 cells cm−2 for 3 h in serum-containing plating medium (MEM with 10% FBS, 0.6% added glucose, 0.08 mg ml−1 sodium pyruvate and 100 UI ml−1 penstrep). Coverslips were then transferred, cells down, to Petri dishes ...
Obesity, associated with the intake of a high-fat diet (HFD), and anxiety are common among those living in modern urban societies. Recent studies suggest a role of microbiome-gut-brain axis signaling, including a role for brain serotonergic systems in the relationship between HFD and anxiety. ...
Cardiomyoblasts (H9C2 cell line) were purchased from Bioresource Collection and Research Center (BCRC) and were maintained in a proliferative state (i.e., undifferentiated condition) by culturing with DMEM (high glucose) medium (11965-084, GIBCO) at 37 °C under 5% CO2. The p‐Cresyl sulfate...
mannose demonstrated a well-balanced reducing power with a more stable rate than glucose and xylose (Additional file1: Fig. S2D). It was in agreement with the observation from cyclic voltammetry (Additional file1: Fig. S3) and amperometry (Fig.1F), where glucose, mannose, and xylose display...
Instead, the current work uses biomass-derived formic acid as a reductant to in situ generate H+/H− species on Pd/HPC–NH2 catalyst, realizing the selective HDO of benzyl ketones from mixed oxygenates under ambient conditions. Therefore, an environmentally friendly route to generate valuable ...
1). Furthermore, control experiment with glucose was also performed to analyze if the random INU1 gene integration into Y. lipolytica genome, did not affect growth of the resulted transformants (Fig. 1). No difference was observed for all analyzed strains in both, YNB medium with glucose ...
Inflammation Determines the Pro-Adhesive Properties of High Extracellular D-Glucose in Human Endothelial Cells In Vitro and Rat Microvessels In Vivo Background Hyperglycemia is acknowledged as an independent risk factor for developing diabetes-associated atherosclerosis. At present, most therapeutic app......
Obesity is a prominent risk factor for male infertility, and a high-fat diet is an important cause of obesity. Therefore, diet control can reduce body weight and regulate blood glucose and lipids, but it remains unclear whether it can improve male fertil
Using in vitro 2-week culture of tenocytes, we found that expression of tendon-related genes, including Egr1, Mkx, TGF-β1, Col1a2, and Bgn, was significantly decreased in HG culture and that higher glucose consumption occurred. Down-regulation of Egr1 by siRNA decreased Scx, Mkx, TGF-...