Results: MTHFR 677 TT genotype has no significant association with the glucose levels and GDM risk, with an adjusted OR of 1.105 (95% CI 0.853, 1.431; p=0.452) and an adjusted PR of 1.050 (95% CI 0.906, 1.216; p=0.518) compared to the wildtype CC group. ...
Methods: During the period of initial tumour progression, MMTV-PyMT (MMTV-polyoma virus middle T) transgenic mice were fed with normal diet and high folic acid diet. Results: We found that PyMT-induced breast tumours highly express the cancer-specific folate receptor (FR), a feature they ...
Nutritional (iron, folic acid, or vitamin B 12 deficiency [pernicious anemia]) Gastrointestinal blood loss (ulcers, colon cancer) Kidney problems Blood loss (from trauma or surgery) Red blood cell synthesis problems (bone marrow disorders, genetic disorders such as sickle cell anemia) Bone marrow...
As a natural substance, as a result, small molecular weight folic acid folic acid to the body with high affinity, as well as the soluble enzymes exist, such as the stability under conditions that are characterized by their carrier for the delivery system provides a target for route of adminis...
Results: We found that PyMT-induced breast tumours highly express the cancer-specific folate receptor (FR), a feature they share with several human epithelial cancers in which expression of FRα correlates with tumour grade. Mice receiving a high folic acid diet displayed a significantly increased ...
These null results for women are consistent with those previously reported in randomized trials composed primarily of men with preexisting vascular disease.3 In the Heart Outcomes Prevention Evaluation Trial (HOPE) 2,5 the same regimen of folic acid, vitamin B6, and vitamin B12 failed to significa...
Iron-folic acid IQR: Interquartile range LMP: Last menstrual period MUAC: Mid-upper arm circumference WASH: Water, sanitation and hygiene WHO: World Health Organization References World Health Organization. Prevalence of anaemia in pregnant women (aged 15-49) in 2019. 2024. https://...
As such, active targeting using the folic acid small molecule was pursued. As mentioned previously, the cell surface FRα receptor is overexpressed in the majority of both primary and recurrent HGSOC tumors. The selection of FRα as the target of choice was informed by literature demonstrating ...
Items Standards Results Conclusions Appearance White powder or pale white powder. White powder Complies Identification (1) Wave length (nm) Max.Absorbace290nm aqueous solution. (1)Wavelength(nm)Max. Absorbance 290nm Complies (2)Dissolved in acetone, by addition of hydrochloric acid, the sol...
The treatment with folic acid and vitamin B12 results in a significant decrease of tHcy. After individual HD by high-flow dialyzer, there is a significant, but temporary decrease of tHcy concentration in plasma. There is no significant difference in the efficiency on pre-dialysis tHcy ...