Five High-Cost Patient Groupsdoi:10.1007/s11606-017-4105-zJohn M. WestfallEugeneKim GriswoldEugeneSpringerJournal of General Internal Medicine
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a single point mutation, p.R691A, in Cas9 (high-fidelity (HiFi) Cas9) retained the high on-target activity of Cas9 while reducing off-target editing. HiFi Cas9 induces robust AAV6-mediated gene targeting at five therapeutically relevant loci (HBB,IL2RG,CCR5,HEXB, andTRAC) in human CD34+...
China plans to train more than 150,000 general practitioners during the five years until 2020 to cope with a national shortage, according to a document unveiled Tuesday. Int'l training on high-speed trains held in central China More than 30 railway staff from Kazakhstan, Kyrgyzstan and Uzbekista...
Despite this level of subjectivity, availability metrics should still be concretely defined in the SLAs that service providers offer their customers. For example, if an SLA promises 99.999% availability (five nines), customers can expect the service to be unavailable for the following amounts of ti...
Interposition grafting (four, vein; one, prosthetic) was used in five patients at high risk (two, repeat operation; two, cervical radiation therapy; one, high bifurcation). Intraoperative completion ultrasound scans were obtained in all but two patients. Perioperative β-blockade was used ...
Nadir and current counts of CD4 + T-cells (CD4 + count) had a median of 304 (IQR 208–400) and 577 cells/mm3 (IQR 426–750), respectively. One-hundred eighty-five patients/204 (90.7%) were already on cART at enrolment (median duration: 4.0 years, IQR 1.4–9.2) and most...
Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study. Lancet. 2017;390(10107):2050-2062. doi:10.1016/S0140-6736(17)32252-3 PubMedGoogle ScholarCrossref 20. Fernandez-Mendoza J,...
Three are part of the cluster involving the private dinner function at SAFRA Jurong on Feb. 15. Five are imported cases and one is linked to a previous case. The ministry also said that a total of 91 patients were still in the hospital and nine of them are under intensive care. ...
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