Perimenopause and menopause.During perimenopause (the period before menopause) and menopause, your levels of estrogen (particularly the type called estradiol) drop significantly. This also happens if you have your ovaries removed or damaged before age 40, resulting in early menopause. ...
Clinical studies in post-menopausal women have also shown that estrogen replacement is associated with maintaining cognitive function in older age, and progesterone may counteract the benefit of estradiol’s cognitive enhancing effect64,65,66. We note, however, that although most hormone replacement the...