Estrogen mediates metabolic syndrome-induced erectile dysfunction: a study in the rabbit. The journal of sexual medicine. 2014;11:2890–902. Article CAS Google Scholar Filippi S, Vignozzi L, Morelli A, Chavalmane AK, Sarchielli E, Fibbi B, Saad F, Sandner P, Ruggiano P, Vannelli GB. ...
cell proliferation, circadian rhythm and Wnt signaling. Thus, our data bring in a role of sex hormones in the basal regulation of these pathways in colon. Intriguingly, we found that estrogen treatment in males indeed regulated the immune response, cell proliferation and rhythmic processes in colon...
Scientific evidence highlights the influence of biological sex on the relationship between stress and metabolic dysfunctions. However, there is limited understanding of how diet and stress concurrently contribute to metabolic dysregulation in both males and females. Our study aimed to investigate the combin...
Reduced vasorelaxation to estradiol and G-1 in aged female and adult male rats is associated with GPR30 downregulation Previously, we reported that chronic activation of the estrogen receptor GPR30 by its selective agonist G-1 decreases blood pressure in ovariectomized hype... SH Lindsey,ASD Silva...
Eleven studies (N = 4,843,598) analyzed the role of abnormalities in the androgen-to-estrogen ratio as a risk factor for MBC. Conditions associated with increased MBC risk include Klinefelter's syndrome (relative risk, RR = 29.64), obesity (RR = 1.98), orchitis/epididymitis (RR = 1.84),...
Studies have shown that androgen and estrogen can affect glucose/lipid metabolism in peripheral organs (e.g., the liver) through differential regulation of the HPA axis43,44. Therefore, this sex disparity in metabolic programming by PEE was probably related to the effects of sex hormones on ...
Estrogen-sensitive human breast cancer cells (ZR-75-1) were incubated with the 3H-labeled adrenal C19-delta 5-steroids dehydroepiandrosterone (DHEA) and it... R, Poulin,D, Poirier,Y, Merand,... - 《Journal of Biological Chemistry》 被引量: 0发表: 2021年 Sleep biological rhythms in norma...
A genomic view of estrogen actions in human breast cancer cells by expression profiling of the hormone-responsive transcriptome Estrogen controls key cellular functions of responsive cells including the ability to survive, replicate, communicate and adapt to the extracellular milieu... C Luigi,S Claudio...
in the ratio of testosterone to estradiol, an estrogen-related hormone. Numerous studies found that, compared to infertility patients without high BPA levels, women seeking treatment for infertility had lower estradiol levels, fewer egg cells, lower rates for the implantation of the fertilized egg, ...
Hyperglycemia and hyperinsulinemia, as encountered in patients with type II diabetes, have been shown to stimulate vascular smooth muscle cell (VSMC) proliferation, a paramount feature in atherosclerosis. Female sex hormones, such as estrogen, have been suggested to inhibit VSMC proliferation. However...