Estrogen is among the most essential hormones created by the ovaries and is responsible for the secondary sex characteristics of women: the menstrual cycle, breast growth, body form. What most people do not realize is that males also have a certain level of estrogen inside their own body, but...
Current literature indicates testosterone promotes GBM cell proliferation, while estrogen and progesterone effects vary with receptor subtype and hormone concentration, respectively. Conclusion: Sex hormones and genetics likely exert influence on GBM development and progression that may compou...
The impact of sex and 13-week HFD were characterized according to standard metabolic and endocrinologic measurements, including weight gain, fat distribution, fasting glucose, insulin, and circulating estrogen levels. HFD-induced weight gain was significantly higher in males compared to females (Fig. ...
Estrogen levels may contribute to sex differences in response to DIO. Indeed, estrogens protect against increased adiposity and obesity through satietogenic effects. Estradiol suppresses feeding by enhancing the potency of other anorectic signals, such as cholecystokinin, leptin, BDNF, and by decreasing...
Dr. Peri (who is on Florida Governor Ron DeSantis’ election committee) suspects that the recent increase in male transgenderism is primarily due to an influx of estrogen (from birth control pills) found in recycled drinking water. If this is true, we need to improve our water recycl...
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative Randomized Controlled Trial JAMA., 288 (2002), pp. 321-333 Google Scholar 206. The HOPE and HOPE-TOO Trial Investigators Effects of long-term vitamin E supplementation...
Biological factors may also contribute, as hormones, particularly estrogen in women, have been shown to exert a protective effect against IS by dilating blood vessels, improving blood flow and induction of anti-inflammatory factors thus reducing the risk of atherosclerosis [34, 35]. Furthermore, ...
Additionally, some studies suggest that endogenous estrogen in women may have a protective effect against CRC, and the use of oral contraceptives may further reduce CRC risk in women [62,63,64]. Studies consistently show higher CRC incidence, mortality, and DALY rates in men than women [65, ...
Negatively enriched gene sets found in both sexes included those associated with cell proliferation and cancer, estrogen responsiveness, and bile acid metabolism. Additionally, male mice had positive enrichment of gene sets associated with myogenesis, muscle development and intracellular calcium dynamics, ...
Estrogen in women, however, “has protective effects, which reduces LDL levels while increasing HDL levels,” Edison said. “Following menopause, the risk of having heart problems begins to increase in women. The protective effect of estrogen pre-menopause may explain why women face problems a de...