"Clearly, in studies of this kind, males matter," she said. According to the CDC, monomethyl pthalate is excreted in the urine of people exposed to dimethyl phthalate, which is used in manufacturing rocket propellant andconsumer productssuch as insect repellents and plastics. Mono-n-butyl pht...
Estradiol interacting with ERα is a negative regulator of adipocyte hypertrophy65,66. Thus, it is plausible that estrogen signaling becomes downregulated in adipose tissue as a means to increase adipocyte lipid storage in response to sucrose intake. In liver, estradiol has been shown to recruit ...
Sexual behavior and serum levels of prolactin, testosterone, and estradiol in young and old rhesus males It has been suggested that increased prolactin levels may contribute to decreased libido in aging male primates. To test this hypothesis, the association o... KC Chambers,CH Phoenix 被引量: ...
Reduced vasorelaxation to estradiol and G-1 in aged female and adult male rats is associated with GPR30 downregulation Previously, we reported that chronic activation of the estrogen receptor GPR30 by its selective agonist G-1 decreases blood pressure in ovariectomized hype... SH Lindsey,ASD Silva...
Many upregulated genes are modulated by estradiol (Figure XVIII in the Data Supplement), and sexually dimorphic differences in cardiac cellularity after AngII treatment were detected by flow cytometry (Figure VIII in the Data Supplement). Moreover, fibrosis developed at specific anatomic loci to ...
1A). As a consequence, males had a substantially lower SAT/VAT ratio (Fig. 1B). A low SAT/VAT ratio has been correlated to poor metabolic outcomes. As expected, female mice had significantly higher circulating estradiol levels compared to males during both CD and HFD (Fig. 1B). ...
Furthermore, their estradiol levels were extremely low. These sterile females displayed neither sexual behavior nor female nuptial coloration despite their rapid growth compared to normal females. In the present study, we induced the sterilization of male tilapia by HT and cultivated these individuals ...
exist in cerebral vessels. One mechanism behind the sex differences we observed might be the influence of sex hormones. ANXA1 is regulated by estrogens in multiple cell types, including microglia. In vitro studies using primary microglia cultures from female mice have shown that estradiol treatment ...
EstradiolUreaTestosterone膳食脂肪类肾多囊The effect of a high level of dietary fat on renal cyst disease was examined in the Han:SPRD-cy rat model of polycystic kidney disease. Control and diseased rats at 4 wk of age were fed either a low fat or high fat diet (5 or 20 g/100 g diet...
4, Jian-Zhong Sheng2, 3, Feng-Tao Shi1, 4, # & He-Feng Huang1, 2, 4, # While the intrauterine environment is essential for the health of offspring, the impact of high maternal serum estradiol (E2) on lipid metabolism in offspring and the mechanisms are ...