The aim of the study was to compare the efficacy of high-dose rosuvastatin, low-dose rosuvastatin plus fenofibrate and low-dose rosuvastatin plus omega-3 fatty acids with regard to the lipid profile in patients with mixed hyperlipidemia. The primary endpoint was changes in non-high density ...
2250ChinMedJ2012;125fl3):2250—2254OriginalarticleEffectofcoronaryelevationhigh--doserosuvastatinloadingbeforepercutaneousinterventioninfema..
(TC,LDL-C,TG) levels of high-dose group decreased more significantly than low-dose group(all P0.01).Conclusion High-dose rosuvastatin was not only to play the rule of regulation of blood lipids,but also to be more effective in reducing serum Hcy and hs-CRP levels in elderly unstable ...
Effects of different doses of atorvastatin, rosuvastatin, and simvastatin on elderly patients with ST-elevation acute myocardial infarction (AMI) after per... Objective To conduct a randomized double‐blind prospective study to investigate effect of different doses of atorvastatin, rosuvastatin, and sim...
Early high-dose rosuvastatin for contrast-induced nephropathy prevention in acute coronary syn- drome : resuhs from the PRATO-ACS study ( protective effect of ro- suvastatin and antiplatelet therapy on contrast-induced acute kidney injury and myocardial damage in patients with acute coronary syn- ...
Methods Three hundred and fifty patients with stable angina who underwent elective PCI were randomly assigned to receive a pre-procedural reloading dose of Rosuvastatin (40 mg) (Rosuvastatin Group—RG n = 175) or Atorvastatin (80 mg) (Atorvastatin Group—AG n = 175) and a ...
However 3 months administration of both starting dose of rosuvastatin (10 mg) and standard dose of fenofibrate was similarly neutral relative to CPR, IL-6 and fibrinogen levels. This can reflect true absence of marked effect or be a consequence of low baseline values of these markers of ...
High-dose statin therapy is cost effective for preventing cardiovascular events in patients with acute coronary syndromes (ACS), but may not be so for patients with coronary artery disease (CAD), report researchers from the US. They developed a Markov model to compare high-dose with conventional...
Patients Between November 2002 and October 2003, 507 patients had a baseline IVUS examination and received at least 1 dose of study drug. After 24 months, 349 patients had evaluable serial IVUS examinations. Intervention All patients received intensive statin therapy with rosuvastatin, 40 mg/d. Mai...
(0.7%), and nausea 10/1497 (0.7%).Conclusions:In this study in patients with primary hypercholesterolemia in clinical practice, greater reductions in LDL-C levels were achieved with a starting dose (10 mg) of rosuvastatin compared with atorvastatin 10 mg, with more patients achieving European ...