standard-dose quadrivalent influenza vaccine against recurrent hospitalisations and mortality in relation to influenza circulation: a post-hoc analysis of the DANFLU-1 randomised clinical trial. Clinical Microbiology and Infection. Published January 27, 2024. Accessed January 30, 2024. doi:...
High‐dose vaccine is associated with a lower rate of probable influenza and hospital admission due to influenza (SOR: B, retrospective cohort). However, the Centers for Disease Control and Prevention (CDC) does not prefer 1 influenza vaccine formulation over ...
Electron microscopy of influenza virus. Credit: CDC In the largest nursing home study to date on the effect of a high dose (HD) flu vaccine, researchers found that vaccines with four times the antigen of standard flu (SD) vaccines significantly reduced the risk of respiratory and all-cause h...
and many other studies have shown the benefits of influenza vaccination in older adults. Adding to this body of literature, Young-Xu and colleagues’ study assessed the relative vaccine effectiveness of the high-dose influenza vaccine compared...
Safety, immunogenicity, and efficacy of Fluzone High-Dose have been evaluated in adults 65 years of age and older. [See Adverse Reactions (6.1) and Clinical Studies (14)] 11. Fluzone High-Dose Description Fluzone High-Dose (Influenza Vaccine) for intramuscular use is an inactivated influenza...
Antibody response after high dose influenza vaccine (HDIV) approved for age ≥ 65 years, is superior to a standard-dose vaccine in HIV-infected persons. We report the effectiveness data of HDIV compared to the standard dose quadrivalent vaccine (SDIV) in our HIV clinic. METHODS. We ...
The FIM12 study was a head-to-head randomised controlled trial in which 31 989 participants aged 65 years and older were randomly assigned (1:1) to receive either high-dose or standard-dose trivalent inactivated influenza vaccine over two influenza seasons (2011–12 and 2012–13). Data for...
Fluzone®High-Dose Quadrivalent is a vaccine indicated for active immunization for the prevention of influenza caused by influenza A subtype viruses and type B viruses contained in the vaccine. Fluzone High-Dose Quadrivalent is indicated for use in persons 65 years of age and older. ...
This secondary analysis of the INVESTED randomized clinical trial assesses whether high-dose compared with standard-dose influenza vaccine was temporally
The high overall genetic homology between humans and rhesus macaques, coupled with the phenotypic conservation of lymphocyte populations, highlights the potential use of nonhuman primates (NHPs) for the preclinical evaluation of vaccine candidates. For HIV-1, experimental models are needed to identify ...