Aim of present study was to assess the impact of a high-intensity statin therapy on vitamin D levels and platelet function in patients with coronary artery disease. Methods: Patients discharged on dual antiplatelet therapy and high-intensity statins after an ACS or elective PCI were scheduled for...
University of Cambridge, Cambridge, UK; 2Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, UK Background: Trial evidence supports statin use after ischemic stroke and recent American, European and British guidelines recommend high-intensity statins for this ind...
This retrospective cohort study estimates the proportion of patients filling high-intensity statin prescriptions following myocardial infarction who
The meta-analysis included five randomized controlled end-point trials that recruited >1,000 participants each, who were followed up for more than 1year and compared intensive-dose statin therapy versus moderate-dose statin treatment. The main findings of this work were that over a weighted mean ...
Effect of Very High-Intensity Statin Therapy on Regression of Coronary Atherosclerosis: The ASTEROID Trial Prior intravascular ultrasound (IVUS) trials have demonstrated slowing or halting of atherosclerosis progression with statin therapy but have not shown con... M Clearfield - 《Current Atherosclerosis...
Accordingly, we designed the ASTEROID trial (A Study to Evaluate the Effect of Rosuvastatin on Intravascular Ultrasound-Derived Coronary Atheroma Burden) to examine the effects of high-intensity statin therapy on IVUS-derived measures of coronary disease progression. Rosuvastatin is the most recently ...
We recently demonstrated, in a multi-center clinical trial, that statin therapy is associated with dose-dependent reduction in atheroslerotic inflammation (assessed with FDG-PET-CT). Here we conduct a post-hoc, blinded analysis of the images derived from that trial to test the hypothesis that ...
High-Dose Statin Therapy Has Expanded Benefits.The article offers information on the results of a study on the expanded benefits of high-dose statin treatment for patients with coronary heart disease (CHD) and those who are at risk of chronic kidney disease (CKD). It mentions that the data ...
High-dose statin therapy for secondary prevention of stroke: stroke prevention by aggressive reduction in cholesterol levels study review. J Cardiovasc Nurs. ... DW Schwertz,KO Badellino - 《Journal of Cardiovascular Nursing》 被引量: 0发表: 2008年 Design and baseline characteristics of the strok...
Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA. 2006;295(13):1556-1565. doi:10.1001/jama.295.13.jpc60002ArticlePubMedGoogle ScholarCrossref 12. Kini AS, Baber U, Kovacic JC, et al. Changes in plaque lipid ...