We report our results of relapsed/refractory NLPHL patients who received high-dose chemotherapy and autogenic stem cell transplantation (HDC auto-SCT). Seventeen NLPHL patients received HDC auto-SCT (19962014): male 14 and female 3, with median age at diagnosis of 22 years, at HDC auto-SCT ...
In 20 patients with non-Hodgkin lymphoma or breast cancer, high-dose cyclophosphamide induced, during the post-nadir period of rapid leucocyte recovery, on median day 19 about a 30-fold increase in the peak concentration of granulocyte-macrophage (CFU-GM) and erythroid (BFU-E) colony-forming ...
To evaluate the long-term benefit from high-dose chemotherapy (HDCT) with autologous stem-cell transplantation (ASCT), as part of the initial treatment for patients with chemosensitive, high-grade B non-Hodgkin's lymphoma (hg B-NHL), stratified according to the age-adjusted International Prognos...
quality of life of women with chemosensitive metastatic breast cancer treated with 6 cycles of standard induction chemotherapy and then either one consolida- tion treatment with cyclophosphamide 1500 mg/m2, mitoxantrone 70mg/m2, carboplatin 450 mg/m2 + ASCT, or continued stan- dard-dose therapy. ...
A phase II multicenter trial of hyperCVAD MTX/Ara-C and rituximab in patients with previously untreated mantle cell lymphoma; SWOG 0213 Background: Rituximab-hyper-CVAD alternating with rituximab-high-dose methotrexate and cytarabine is a commonly utilized regimen in the United States for m... SH...
A prospective randomized trial of buffy coat vs CD34-selected autologous bone marrow support in high-risk breast cancer patients receiving high-dose chemotherapy. Blood 1997; 90: 4313–4320. CAS PubMed Google Scholar Chabannon C, Cornetta K, Lotz JP et al. High-dose chemo-therapy followed ...
摘要:Willmann, Gabriel. Ultraviolet keratitis: From the pathophysiological basis to prevention and clinical management. High Alt Med Biol 16:277-282, 2015.Ultraviolet keratitis is caused by the toxic effects of acute high-dose ultraviolet radiation (UVR) reflecting the sensitivity of the ocular su...
A dose- and < 0.001 (Fig. 1A). The KEGG pathway analysis of overlapping time-dependent inhibitory effect of B389 on the growth of CAOV3 upregulated DEGs revealed that the cell cycle pathway was the and OV90 cells was observed (Fig. 3C). The colony formation ability of most enriched ...
Patients were re-evaluated before the start of each of the 4 high-dose chemotherapy cycles. All phases were followed by a measurable tumor size reduction with CR in 50% of patients after high-dose cytarabine (HD-Ara-C) and 50% after the final myeloablative phase(s). p-STD indicates after...
Lymphoma Working Party of the European Group for Blood and Marrow Transplantation (2002) Aggressive conventional chemotherapy compared with high-dose chemotherapy with autologous haematopoietic stem-cell transplantation for relapsed chemosensitive Hodgkin’s disease: a randomised trial. Lancet 359:2065–2071....