De Boer RJ,Borghans JAM,Van Boven M,et al.Heterozygote advantage fails to explain the high degree of polymorphism of the MHC. Immunogenetics . 2004de Boer, R. J., Borghans, J. A. M., Van Boven, M., Kes¸mir, C. & Weissing, F. J. 2004 Heterozygote advantage fails to explain...
Given these differences in the properties of CNV and SNP markers, we anticipate that they will vary in their degree of population genetic divergence. To test this hypothesis, we employ genotype data at CNV loci from the HapMap Phase III populations. This has two advantages. The first is that...
phenotype differed both by biometric measures and isotopic niches between most pairs of populations. Although individuals from the northernmost colony are larger than the others, they are genetically similar, indicating a wide reaction norm for this species. Our results indicate the Southwestern Atlantic ...
A subset of 1656 Wytham individuals with confirmed first degree pedigree links (genotyped parents and/or sibs and/or offspring) and confirmed sex were chosen for constructing the UK great tit linkage map (see Supplementary Methods for more details). For the UK population, complex pedigrees were ...
γ-Ray diffractometry is a convenient method for studying the degree of perfection of large "as-grown" single crystals without the need of precedent cutting or surface treatments. By means of a double crystal arrangement the angular resolution in γ-ray diffractometry has been improved by at least...
The aim of this study was to investigate effective long-distance dispersal and adaptive divergence in the fen orchid (Liparis loeselii (L.) Rich.). We used amplified fragment length polymorphism (AFLP)-based assignment tests to quantify effective long-distance dispersal at two different regions in...
(one of the reference cohorts of theHapMap projectfor determining common haplotypes around the world), the attributable variance in AGT concentration in plasma was 0.64 for the rs5051 variant, indicating a very high degree of heritability. But there are many other common variants in the same ...
The advances of hyperspectral technology provide a new analytic means to decrease the gap of phenomics and genomics caused by the fast development of plant genomics with the next generation sequencing technology. Through hyperspectral technology, it is p
The FST values for the Daghestani populations were 0.017, 0.146, 0.155 and 0.075 for autosomal, Y-SNP, Y-STR and mtDNA data, correspondingly, indi- cating a significant degree of population differentiation within Daghestan (Table 1). When only ND populations were included in analyses, the FST...
Codons 41–42 and codon 17 mutations, for example, are more severe (based on the degree of hemophthi- sis) than codon 26. Similarly, the deletion allele --SEA/αα results in a serious clinical manifestation of anemia. We propose that requiring thalassemia carrier screening, particularly in...