Current treatments for CKD and fibrosis primarily aim to suppress typical symptoms and usually target single signaling pathway. However, therapeutic outcomes of these treatments are unsatisfactory, which is likely due to the intricate nature of CKD and the presence of fibrotic niches where inflammation ...
< 12 individuals, of which two had severe COVID-19 and were hospitalized, required oxygen (but no mechanical ventilation) and received either a combined treatment with casirivimab, imdevimab and tocilizumab or sotrovimab, two experienced moderate symptoms, and three experienced mild symptoms. ...
Out of 35 (7 buffalo and 28 cattle) breeding bulls of different breeds, 15 (43%) cattle bull died in a short span of 3 weeks. Animals exhibited staggering gait, anorexia, depression and raised body temperature. No mortality occurred in buffalo bulls despite severe nervous symptoms like fro...
These results provide a cellular mechan- ism for the clinical effect of STN HFS in Parkinson's disease, in which STN HFS may silence abnormal bursting patterns of discharge in output regions of the basal ganglia (SNr and EP) associated with the motor symptoms of Parkinson's disease. Both ...
Protein-restricted diets are prescribed in patients with chronic renal failure (CRF) to alleviate uremic symptoms and to slow the progression of CRF. The p... M Aparicio - 《Journal of the American Society of Nephrology》 被引量: 482发表: 2000年 Serum Lipoprotein (a) Levels in Chronic Renal...
[3]. This topic was recently addressed in two comprehensive reviews, which advocated for more research on sex and gender differences in OA risk factors, disease etiology, symptoms, and treatment efficacy [4,5]. In this regard, two recent population-based studies and a systematic review of sex...
Clinical features related to statin-associated muscle symptoms. Muscle Nerve. 2019;59:537–43. Article PubMed PubMed Central CAS Google Scholar Habib SS, Aslam M, Naveed AK, Razi MS. Comparison of lipid profiles and lipoprotein a levels in patients with type 2 diabetes mellitus during oral ...
The 650 control subjects (364 men and 286 women) exhibited normal electrocardiograms at rest and no signs of myocardial ischemia during exercise stress testing; these examinations were performed in control subjects as part of a medical checkup in the absence of cardiovascular symptoms. Among all 1...
(HSCs). In line, the same study also demonstrated that iASPP prevents the induction of apoptosis in HSCs upon cellular stressors such as irradiation [18]. Physiologically, iASPP serves as a checkpoint to maintain cellular integrity, but at the same time high levels of iASPP may facilitate the...
A single nucleotide polymorphism (SNP) is a variation in the DNA sequence that results from the alteration of a single nucleotide in the genome. Atorvastatin is used to treat hypercholesterolemia. It belongs to a class of drugs called statins, which lower elevated levels of total cholesterol (TC...