(2015) Non-cirrhotic Hyperammonemia—When High Ammonia Is not Always from Cirrhosis. Current Hepatology Reports 14 , 25-31 /Kumar S., Asrani S. K. Non-cirrhotic hyperammonemia—when high ammonia is not always from cirrhosis. Current Hepatology Reports . 2015; 14 (1):25–31. doi: 10.1007/...
In the present investigation, cortisol levels were assessed in response to dietary manganese (Mn) at 4, 8, and 12 mg kg−1diet fed toP. hypophthalmus. The fish were reared under normal conditions as well as under the arsenic and ammonia pollution, coupled with high-temperature stress, over...
The study included more than 6,800 patients with cirrhosis—a condition where the liver is scarred from long term damage—andhepatic encephalopathy. The research team's analysis found patients who are younger and have metastatic cancer or depression are less likely to take their medication. The re...
In the present investigation, cortisol levels were assessed in response to dietary manganese (Mn) at 4, 8, and 12 mg kg−1diet fed toP. hypophthalmus. The fish were reared under normal conditions as well as under the arsenic and ammonia pollution, coupled with high-temperature stress, over...
We have previously shown that ammonia induces an elevation of the neuronal tricarboxylic acid cycle activity. Thus, the aims of the present study were to determine if increased levels of ammonia increase GABA synthesis via the indirect pathway in a rat model of HE induced by bile-duct ligation ...
Specifically, glutamine (Gln), the metabolic by-product of ammonia transformation in the brain, is difficult to distinguish from glutamate (Glu) in MR spectra at lower magnetic fields [12]. This is relevant because Gln is accepted to be the main driver in the osmotic changes in the brains ...
In addition to energy production, mitochondria play an important role in other cellular functions such as fatty acid oxidation, anti-oxidant defense, intermediary metabolism including ammonia and glutamate detoxification, synthesis of heme and steroids, cell death process, and autophagy [1]. Recent ...
Samples were separated using an Agilent 1290 Infinity LC Ultra Performance Liquid Chromatography System (UHPLC) HILIC column; column temperature 25 °C; flow rate 0.3 mL/min; mobile phase composition A: water + 25 mM ammonium acetate + 25 mM ammonia, B: Acetonitrile; gradient elution...
The patients in the PEG-Lactulose group received the same amount of oral or rectal Lactulose, plus 280 grams of PEG in 4 liters of water orally as a single dose in 30-120 minutes. Serial physical examinations, hepatic encephalopathy scoring algorithm (HESA), blood level of ammonia, and ...
This study tests the hypothesis that the effect of ammonia on the neuropsychological function in patients with cirrhosis is determined by the ability of the brain to buffer ammonia-induced increase in glutamine within the astrocyte by losing osmolytes like myoinositol (mI) and not by the magnitude...