High-fat diet-fed animals showed fat deposition in the liver and eventually developed steatosis and hepatic damage. Hepatic damage was assessed by measuring the activities of enzyme markers of liver function. Serum ALT, AST and ALP activities are increased when hepatic damage occurs, and we measure...
Intermittent hypoxia (IH) is defined as periodic alternating exposures to hypoxia and normoxia. IH has been associated with obstructive sleep apnea1,2as well as sports training3,4,5. It is of utmost importance to delineate the effects of IH observed in obstructive sleep apnea from the beneficial...
. Other serological parameters, such as total cholesterol (TCHO), alanine transaminase (ALT), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), aspartate transaminase (AST), and low-density lipoprotein cholesterol (LDL-C) were analyzed by an automated clinical chemistry analyzer (...
The serum levels of TG, TC, LDL-C, HDL-C, ALT, Glu and FFA were measured using an automatic biochemical analyser (Hitachi 7080, Japan). Biochemical indicators of liver (TG, TC, FFA, lipase (LPS) activity) function and faecal levels of various lipids (TG, TC, bile acid, and LPS act...
Except for LDL-C, significant differences (P < 0.01) existed in BMI (25.80 ± 3.33 kg/m2 vs 24.09 ± 3.62 kg/m2), WHR (0.89 ± 0.06 vs 0.80 ± 0.06), ALT (26.11 ± 20.27 IU/L vs 18.55 ± 13.34 IU/L), AST (23.27 ...
The serum biochemical indicators, including triglyceride (TG), total cholesterol (CHOL), low-density lipoprotein-cholesterol (LDL-c), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) were detected by a TBA-40FR automatic biochemical analyzer (Toshiba, Jap...
Importance. In phase 2 studies, evolocumab, a fully human monoclonal antibody to PCSK9, reduced LDL-C levels in patients receiving statin
With the increase of TG/HDL-C from the first to the fourth quartile (Q1-Q4), parameters including BMI, DBP, SBP, TG, TC, LDL-C, FPG, SUA, Scr, ALT and AST were all significantly elevated (all P for trend < 0.001). Moreover, the prevalence rates of NAFLD were also ...
Groups that were fed the HF diet showed increase in liver weight, liver fat percentage, and ALT and TNF-α levels, with these liver changes all being characteristic of steatosis, whereas treatment with açai effectively inhibited the increase of these parameters (Table 1). No effect was ...
Residuals of TG, LDL and HDL were calculated by adjusting for sex, body mass index and the first three principal components (PCs) derived from the genetic data to control for potential population structure. The residuals were further inverse-normal transformed; however, it is worth noticing that...