Prepubertal animals presented no differences in these parameters between males and females. Despite this finding, the hepatic expression levels of Bip, Ire1alpha and Xbp1s mRNA were lower in prepubertal males than in females, while in adult animals, they did not differ between sexes. In the ...
In our study, we found that the underlying mechanism of AUB is closely related to the synthesis of steroid hormones, including the metabolism products of common steroids such as pregnenolone, progesterone, 17α-hydroxyprogesterone, and dihydrocortisol. Steroids are a class of biologically active substa...