英文名字 HIF1AN Antibody [Clone HIF1A-84] 供应商 Abgent 产品货号 A-AH10199 产品报价 ￥2870/100 ug 产品说明书 点击查看 购买方式 产品新闻 背景资料 HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits ...
货号:ZY-HIF1a-p 品牌:泽叶生物 产地:上海 样本:血清相关液体 标记物:IgG 应用:仅供科研使用 重组蛋白相关产品报价更多> 产品标题价格产地公司名称更新日期 重组蛋白1α(MEP1a)重组蛋白￥2651/支武汉VIP2年湖北艾普蒂生物工程有限公司2025-02-28询价
生化机理 在C 端转录激活域 (CAD) 的 "Asp-803 "处羟化 HIF-1 alpha。作为氧传感器发挥作用,在常氧条件下,羟化作用可阻止 HIF-1 与转录辅激活因子(包括 Cbp/p300-interacting transactivator)相互作用。通过与 HIF1A、VHL 和组蛋白去乙酰化酶的相互作用参与转录抑制。 宿主种属 兔(Rabbit) 特异性 HIF1...
(cad) . functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of hif-1 with tranional coactivators including cbp/p300- interacting transactivator. involved in tranional repression through interaction with hif1a, vhl and histone deacetylases. hydroxylates ...
HIF1AN silencing offset the negative regulation of miR-429 inhibition on the HIF1A/vascular endothelial growth factor (VEGF) signaling pathway. In vivo experiments showed that depletion of miR-429 attenuated ectopic lesion development in the mouse EM model. Collectively, suppressing miR-429 hinders ...
(CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxy...
MAP1A重组蛋白;高活性/Recombinant human MAP1A protein MAP2重组蛋白;高活性/Recombinant human MAP2 protein MAP4重组蛋白;高活性/Recombinant human MAP4 protein MAP6重组蛋白;高活性/Recombinant human MAP6 protein MAST2重组蛋白;高活性/Recombinant human MAST2 protein ...
Hypoxia-inducible factor-1aPI3K-dRNA interferenceVascular endothelial growth factorHypoxia-inducible factor-1 (HIF-1) plays a critical role in immune and inflammatory responses. One of the HIF-1 target genes is vascular endothelial growth factor (VEGF), which is a potent stimulator of inflammation,...
In LNCaP cells the effect of miR-135b and siHIF1ANs seems more potent than siAR. 4. Discussion The questions of hormone receptor status and responsiveness to endocrine therapy in BCa and PCa are addressed in the clinic at the time of diagnosis and during treatment. Further understanding of ...
Hypoxia-inducible factor-1 (HIF-1) plays a critical role in immune and inflammatory responses. One of the HIF-1 target genes is vascular endothelial growth factor (VEGF), which is a potent stimulator of inflammation, airway remodeling, and physiologic dysregulation in allergic airway diseases. Usi...