HFE-145人胃黏膜正常上皮细胞 产品名称: HFE-145人胃黏膜正常上皮细胞 产品类别:人/贴壁 品牌: OTWO(华拓) 货号: HTX3503 规格: 一株(2×10⁶cells)详细信息 产品名称: HFE-145人胃黏膜正常上皮细胞 传代比例: 1:2至1:4 说 明 书: 提供详细说明书 质量保证: 1. 细胞为三代以内,活体。运输过程...
氟化油通常用作这类应用的连续相,因为其能够溶解和输送氧气,并且不溶解大多数化学和生化化学物。FluoSurf是一种生物相容性氟化表面活性剂,专为生产单分散油包水液滴而设计和优化。FluoSurf可确保液滴的长期稳定性(即使在极端条件下也是如此)。 详细介绍
The childhood leukemia association possibly results from elevated intracellular iron in lymphoid cells increasing the vulnerability to DNA damage at a critical time window during lymphoid cell development. Interactions of HFE with environmental and genetic factors, most of which are recognized, may play ...
Hela CellsCell MembraneIronDNA PrimersTransferrinRecombinant ProteinsMembrane ProteinsReceptors, TransferrinHFE, the protein mutated in hereditary haemochromatosis type 1, is known to interact with the transferrin receptor (TfR) on the cell surface and during endocytosis [Gross, Irrinki, Feder and Enns...
Hepcidin is a negative regulator of iron absorption and recy- cling, and functions to limit iron release from cells by binding to the iron exporter ferroportin, causing its internalization and degradation.9 All forms of HH reported so far result from defective func- tion or regulation of ...
cells suggests that DMT1 also plays an important role in iron uptake by beta cells [36]. In a study of mice with global or tissue-specific inactivation of theSlc11a2gene that encodes DMT1, the investigators concluded that hepatocytes and most cells (other than placenta, small intestinal ...
Ferritin release by mononuclear cells in hereditary hemochromatosis. J Lab Clin Med., 113 (1989), pp. 145-150 View in ScopusGoogle Scholar 45 E Moura, MA Noordermeer, N Verhoeven, AF Verheul, JJ Marx Iron release from human monocytes after erythrophagocytosis in vitro: an investigation in no...
The role of TfR in iron uptake has been well characterized but the association with HFE was previously unnoticed, perhaps because HFE is not expressed in commonly used cultured cell systems (e.g., HeLa cells, 293 cells; J. N. F, unpublished data), possibly an adaptive response to allow ...
Conversely, a decrease of hepcidin expression favors cell membrane expression of ferroportin, and, in turn, the iron release from cells into the plasma, thus, increasing the transferrin saturation by iron. The regulation of hepcidin expression plays a major role in the maintenance of iron ...