Aberrant expression of 37 representative lncRNAs and 254 protein-coding RNAs was observed in the livers of HFD-fed mice with insulin resistance compared with the livers from control mice. Of these, 24 lncRNAs and 179 protein-coding RNAs were upregulated, whereas 13 lncRNAs and 75 protein-coding...
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both SCSP and d-SCSP reduce body weight, fat and liver hypertrophy, insulin resistance, and serum lipid and inflammatory cytokine levels in HFD-fed mice... - 《Molecular Nutrition & Food Research》 被引量: 3发表: 2018年 Dietary Tomato Pectin Attenuates Hepatic Insulin Resistance and Inflammation...
Miquelianin, the main flavonoid in Folium Netlumbinis, could stimulate WAT beiging in 3T3-L1 cells and iWAT of HFD-fed mice. The potential mechanisms associated with the inhibition of AMPK/DRP1/mitophagy and remodeling of gut microbiota profile (Fig. 9). Our findings shed new light on the ...
mitigates hepatic steatosis without damage to the kidney.Miquelianin retains beige fat formation by down-regulating AMPK/DRP1/mitophagy.Miquelianin beneficially improves high-fat-diet (HFD)-induced dysbiosis in obese mice.Miquelianin may be an important ingredient in the beige-promoting effects of ...
(HFD) ‑induced metabolic symptoms, it was hypothesized that coffee intake could delay the onset of obesity related‑cataract; however, the effect of coffee consumption on this type of cataract remains unknown. Four‑week‑old male C57BL/6JJms SLC mice were divided into two groups and ...
A therosclerosis-prone mice (males and females) lacking properdin were fed low fat or high fat diets for 12 weeks. Atherosclerosis burden was assessed in aortae and at aortic roots. (A) lesion burden in aortae identified by Oil Red O staining (stains l...
Trehalose is a functional disaccharide that has anti-metabolic activities such as suppression of adipocyte hypertrophy in mice and alleviation of impaired glucose tolerance in humans. Trehalase hydrolyzes trehalose in the small intestine into two glucose molecules. In this study, we investigated whether ...
Mice were kept at 25 ± 1 °C, 45–55% RH and a 12:12 light/dark cycle and acclimatized for 7 days. All the experiments were conducted according to the guidelines of the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEAs), India. They were ...
Maternal Diet Supplemented with Methyl-Donors Protects against Atherosclerosis in F1 ApoE−/− Mice (ApoE(-/-)) deficient dams with the MS diet during pregnancy reduces atherosclerotic plaques in F1 mice that were fed high fat diet (HFD) after ... C Delaney,SK Garg,C Fernandes,... - ...