尽管右向左分流会适当降低动脉氧饱和度,但左心搏出量的增加还是会整体增加心肌及肾脏灌注,强化利尿等多种机制来改善患者右心衰竭症状。 2021年ESC心力衰竭管理指南发布,将射血分数中间值心衰(Heart failure with mid-range ejection fraction,HFmrEF)改名为射血分数轻度降低的心衰(Heart failure with mildly reduced e...
HFmrEF, heart failure with mid‐range ejection fraction; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction. Rate per 100 patient‐years. All reported HR were adjusted for...
Methods TRANSFORM-HF was an open-label, pragmatic, randomized trial of 2,859 patients hospitalized for HF (regardless of ejection fraction) across 60 hospitals in the United States. Patients were randomized in a 1:1 rati...
根据左心室射血分数(left ventricular ejection fraction,LVEF),分为射血分数降低的心衰(heart failure with reduced ejection fraction,HFrEF)、射血分数保留的心衰(heart failure with preserved ejection fraction,HFpEF)和射血分数中间值的心衰(heart failure with mid-range ejection fraction,HFmrEF)。根据心衰发生的...
Efficacy of empagliflozin in heart failure with preserved versus mid-range ejection fraction: a pre-specified analysis of EMPEROR-Preserved Article Open access 05 December 2022 Main The costs of conducting clinical trials have risen substantially over time, leading to calls for novel study designs to...
Whether the sodium–glucose cotransporter 2 inhibitor dapagliflozin reduces the risk of a range of morbidity and mortality outcomes in patients with heart failure regardless of ejection fraction is unknown. A patient-level pooled meta-analysis of two tri
HF with a LVEF ≤ 35% or HF with preserved ejection fraction (NYHA class II–IV, elevated natriuretic peptides (NP), left ventricular hypertrophy (LVH) or left atrial enlargement (LAE) or diastolic dysfunction BNP ≥ 100 pg/mL or NT proBNP ≥ 400 pg/mL Subjects with the ...
they affected a large part of the ionosphere. That day, V/UHF bands were closed at high latitudes with auroras in Alaska and up to mid latitudes (>55° with Kp=8). This time the effects of the CME created a radio blackout up to 15 MHz where the attenuation reached till ~35 dB; ...
“Dapagliflozin not only reduced CV death and hospitalizations, but also significantly improved symptoms, physical limitations and quality of life in patients with heart failure with reduced ejection fraction,”Mikhail Kosiborod, MD, FACC, FAH...
1.Subodh Verma, et al. 2023 AHA. Abstract 14120: Characteristics, Outcomes and Treatment Response With Dapagliflozin Across the Range of Ejection Fraction in People With HF and a History of CABG Surgery: A Pooled Analy...