MP Hermans,JL Gala,M Buysschaert.The MTHFR CT polymorphism confers a high risk for stroke in both homozygous and heterozygous T allele carriers with Type 2 diabetes.Diabet. Med. 2006The MTHFR C677T polymorphism confers a high risk for stroke in both homozygous and heterozygous T allele ...
Contraception- related deep venous thrombosis and pulmonary embolism in a 17-year-old girl heterozygous for factor V leiden, prothrombin G20210A mutation, MTHFR C677T and homozygous for PAI-1 mutation: report of a family with multiple genetic risk factors and review of the literature. ...
Aortic thrombus and acute pulmonary embolism in an individual heterozygous for the MTHFR C677T mutation. Rev Esp Cardiol. 2010;63:1366.D'Amato N, Correale M, D'Agostino C. Aortic thrombus and acute pulmonary embolism in an individual heterozygous for the MTHFR C677T mutation. Rev Esp ...
A molecular thrombophilia panel revealed the presence of heterozygous factor V Leiden G1691A and methylenetetrahydrofolate reductase C677T gene mutations. OutcomeGeneral precautions to avoid injuries and spontaneous bleeding were advised. MessageLife-threatening bleeding may not be the first finding in ...
Recurrent thrombophlebitis in a colon cancer patient with C677T heterozygous genotype for MTHFR treated with 5-fluorouracil-based adjuvant chemotherapy[J].Chemotherapy 2004,50(04).Schiavon G,Vincenzi B,Santini D,et al.Recurrent thrombophlebitis in a colon cancer patient with C677T heterozygous...
This variant has not been reported in GnomAD database and is a novel variant as per controlled from ClinVar and HGMD mutation databases Also coagulation tests were done Patient was heterozygote for the prothrombin mutation (FXIII) and homozygote for MTHFR C677T mutation. The patient has normal ...
Hermans M, Gala JL, Buysschaert M (2006) The MTHFR C677T polymorphism confers a high risk for stroke in both homozygous and heterozygous T allele carriers with Type 2 diabetes. Diabetic Med 23: 529- 536.The MTHFR CT polymorphism confers a high risk for stroke in both homozygous and ...
Acquired Thrombotic Thrombocytopenic Purpura (TTP) in a patient with heterozygous MTHFR C677T mutation and hyperhomocysteinemia – a case reportAcquired Thrombotic Thrombocytopenic PurpuraMTHFR C677T mutationdoi:10.1016/j.achaem.2015.07.112elsevier
Coagulopathy evaluation revealed C677T/A1298C compound heterozygous genotype for MTHFR, and plasma homocysteine level after 6 months of folate and multivitamin supplementation was 10 microM (reference range 4-10 microM). The patient was diagnosed with BRAO and maintained on coumadin therapy....
Investigation of subsequent fetal losses revealed homozygosity for the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism associated both with fetal loss and with osteoporosis (OP). Because her neonatal unilateral blindness and OP were suggestive of loss-of-function mutation(s) in the gene ...