Heterologous Expression and Delivery of Biologically Active Exendin-4 by Lactobacillus paracasei L14Expression and Delivery of Exendin-4 by Lactobacillus Straindoi:10.1371/journal.pone.0165130Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, is an excellent therapeutic peptide drug for ...
The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells wit...
neoantigen score30(Extended Data Fig.2a), the 20 highest ranking mutations were selected for inclusion in a codon-optimized vaccine expression cassette. The same expression cassette was inserted into both patient-specific vaccine vectors for manufacturing. Patient-specific vaccines were successfully manufac...
The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells wit...
The E. coli maltose binding protein (MBP) has been utilized as a translational fusion partner to improve the expression of foreign proteins made in E. coli. When located N-terminal to its cargo protein, MBP increases the solubility of intracellular proteins and improves the export of secreted ...