Nitric oxide (NO) is a well-known mediator of auto-immune processes. In the thyroid gland, it is produced in response to interleukin 1 (IL-1) and may mediate cytokine action at an early stage of autoimmune thyroiditis. In this study, we have investigated whether NO is involved in ...
Baylin, SB, Mensensohn, G: Medullary thyroid carcinoma: A model for the study of human tumor progression and cell heterogeneity. In: Coffey, DS, Baylin, SB (eds) Tumor Cell Heterogeneity: Origins and Implications. Academic Press, New York, 1982, pp 9–29 Google Scholar Jollos, V: Exper...
Genetic Alterations in Medullary Thyroid Cancer: Diagnostic and Prognostic Markers. Medullary thyroid carcinoma (MTC) is a rare calcitonin producing neuroendocrine tumour that originates from the parafollicular C-cells of the thyroid gland... Taccaliti,A.,Silvetti,... - 《Current Genomics》 被引量...
There was a large heterogeneity between the studies regarding study design, estimation of the dose to the thyroid gland and definition of endpoints. In ... MJ Boomsma,HP Bijl,JA Langendijk - 《Radiotherapy & Oncology Journal of the European Society for Therapeutic Radiology & Oncology》 被引量...
Function of the primary cilium Since their discovery in the kidneys and the thyroid gland by Zimmermann in 1898, primary cilia have been considered as vestigial organelles, without a specific function, due to their lack of motility and their absence in several cells during mitosis (27). In 1975...
Isotopic techniques have been used to study phenomena in the geological, environmental, and ecological sciences. For example, isotopic values of multiple elements elucidate the pathways energy and nutrients take in the environment. Isoscapes interpolate
A Metabolic Phenotype Based on Mitochondrial Ribosomal Protein Expression as a Predictor of Lymph Node Metastasis in Papillary Thyroid Carcinoma Metabolic reprogramming has been regarded as an essential component of malignant transformation. However, the clinical significance of metabolic heterogeneity remains ...
Intra-tumor heterogeneity is one of the biggest challenges in cancer treatment today. Here we investigate tissue-wide gene expression heterogeneity throughout a multifocal prostate cancer using the spatial transcriptomics (ST) technology. Utilizing a nov
The enzymic heterogeneity of the lysosomal system has been demonstrated earlier. This study was concerned whether or not the lysosomes of the two outer zon
Over the past years, optical imaging techniques, such as parathyroid autofluorescence, indocyanine green (ICG) angiography, and laser speckle contrast imaging (LSCI) have been employed to save parathyroid glands during thyroid surgery. This study provides an overview of the utilized methods of...