Heterocyclic compounds containing thiazole ring as important material in medicinal chemistryThiazoleMetal complexesBiological activityHeterocyclic compoundThiazoles are among the most important heterocyclic compounds that contain sulphur at positions 1 and nitrogen at positions 3 in a 5-membered ring. Thiazoles...
2. Heterocyclic-based azo compounds in medicinal chemistry Heterocyclic-based azo compounds can inhibit the growth of various parasites [14,15], including SM [[16], [17], [18], [19]]. These scaffolds improve physical-chemical profiles and generate anti-schistosomal effects by enabling SAR optim...
Also included are new sections dealing explicitly with a number of topics important in the heterocyclic context: (i) heterocyclic fluorine compounds, (ii) isotopically labeled heterocycles, and (iii) the modern techniques of solid-phase chemistry, microwave heating and flow reactors. ...
their interest toward greener approaches for the development of medicinal products, as they minimize the production of waste and costs of the synthetic ... S Pathania,RK Rawal - 《Chemistry of Heterocyclic Compounds》 被引量: 0发表: 2020年 Heterocyclic compounds, their production, and medicaments ...
摘要: 本发明提供了式(I)所代表的杂环化合物或其盐,其具有RORγt抑制作用,其中,每个符号如说明书所定义. Heterocyclic compound or a salt thereof represented by the present invention provides compounds of formula (the I), which inhibit RORyt, wherein each symbol is as defined in the specification....
For the cell viability experiments, cells were seeded in 96-well plates at 3 × 104 cells per well in 50 µL of complete medium. After they had adhered to the culture plate, the cells were exposed to the different platinum compounds (NHC-Pt-PEI or oxaliplatin as control) during 45 ...
Novel antidiabetic compounds, their tautomeric forms, their derivatives, their steroisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and p
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The Chemistry of Heterocyclic Compounds, Part 1, Volume 15, Heterocyclic Systems with Bridgehead Nitrogen Atoms 078240, PUJARI H K ET AL: " Heterocyclic systems containing bridgehead nitrogen atoms. Part LXVIII. Reaction of 5-fluorobenzimidazole-2-thione with chloroacetic acid: studies of orientation ...
Compounds of Formula I are antagonists of VLA-4 and/or α4β7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of asthma,...