This article will help prepare nurse practitioners to recognize key clinical features of these syndromes and understand testing criteria. Additionally, this article discusses barriers to diagnosing hereditary cancer syndromes and the role of primary care nurse practitioners in ordering genetic tests and ...
in an OB/GYN setting meet criteria for hereditary cancer testing.1 1. DeFrancesco, et al. 2018 What is MyRisk with RiskScore? MyRisk can help you and your provider understand your risk of developing 11 different types of cancer, including breast cancer. It can also provide important informat...
Myriad Genetics, Inc. announced a study indicating that the use of its online screening tool, MyGeneHistory®, alongside a virtual education program, significantly increased the completion rates for hereditary cancer testing among patients. The research, published in Obstetrics & Gynecology ...
Testing only patients who meet guidelines criteria may lead to missing up to 42% of patients with an inherited disease-causing (pathogenic) variant.1 Genetic testing for all patients with cancer helps provide vital genetic information that can help guide their treatment.128...
Germline heterozygous pathogenic variants (PVs) in TP53 cause Li-Fraumeni syndrome (LFS), a condition associated with increased risk of multiple tumor types. As the associated cancer risks were refined over time, clinical criteria also evolved to optimiz
Nearly 1 in 4 patients1meet criteria for hereditary cancer testing MyRisk is more than a test Delivers personalized care plans The MyRisk Management Tool offers personalized guidance for patients and providers to work together to reduce risk of developing cancer or detect it at an earlier, more ...
For patients meeting National Comprehensive Cancer Network criteria for clinical genetic testing, providers should consider expanded panels to provide a more complete assessment of one's genetic risk. The continued use of expanded panel testing in the clinical setting will help inform optimal management ...
Breast cancer (BC) is the commonest cancer in South African women. A proportion are associated with a pathogenic or likely pathogenic (P/LP) variant in a B
The aim of this study was to determine the clinical and molecular characteristics of 2,079 patients who underwent hereditary cancer multigene panel testing. Panels included comprehensive analysis of 14–22 cancer susceptibility genes (BRCA1 and BRCA2 not
Having a patient-initiated model can reduce the genetics referral barrier that has been observed in cancer genetics. It can also reduce non-genetics healthcare providers’ reported genetic testing barriers of limited genetics knowledge, uncertainty with hereditary cancer t...