Perjeta+Herceptin固定剂量组合是一种新型的SC剂型,其将Perjeta、Herceptin与Halozyme Therapeutics公司的Enhanze药物递送技术结合在一起,与静脉注射相比,可为患者提供用药便利。 FeDeriCa是一项国际性、多中心、双臂、随机、开放标签研究,在正接受新辅助治疗(术前)和辅助治疗(术后)的500名HER2阳性早期乳腺癌(eBC)患者中...
如果获得批准,这款新的Perjeta与Herceptin固定剂量组合SC注射制剂将提供一种替代生物仿制药Herceptin与Perjeta组合的新疗法,这将潜在地减少生物仿制药对罗氏HER2特许专营权的影响。 参考来源: 1、Roche’s fixed-dose subcutaneous combination of Perjeta and Herceptin showed non-inferiority when compared to intravenous ...
If you are receiving Perjeta for treatment of HER2+ early breast cancer, you may continue treatments with Herceptin every 3 weeks for one year (18 cycles total). For the treatment of HER2+ metastatic breast cancer, you will receive Perjeta and Herceptin until the medicine no longer controls yo...
This is a patient friendly review of the cancer drug Herceptin (or, Trastuzumab), commonly used for HER2 positive breast cancer, often in conjuction with Perjeta (or Pertuzumab), even by injection (Phesgo); Herceptin can sometimes be used for stomach cancer or bowel cancer if the patient is ...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook Herceptin Medical Wikipedia Related to Herceptin:HER2 Her·cep·tin (hər-sĕp′tn) A trademark for the drug trastuzumab. American Heritage® Dictionary of the English Language, Fifth Edition. Copyright ©...
It is to be used in combination with trastuzumab and other chemotherapy prior to surgery and, depending upon the treatment regimen used, may be followed by chemotherapy after surgery. Following surgery, patients should continue to receive trastuzumab to complete 1 year of treatment. Perjeta’s ...
EirGenix is also developing a biosimilar of Roche’sPerjeta (pertuzumab), a drug that isapprovedas an adjuvant therapy for HER2-positive early breast cancer in combination with Herceptin and chemotherapy. The Taiwanese company is planning a Phase III trial for the biosimilar, as per an ...
Trastuzumab 4 mg/kg is administered alone or in combination with paclitaxel followed by once weekly doses of 2 mg/kg until there is disease progression. Herceptin Metastatic Gastric Cancer The initial dose of trastuzumab is 8 mg/kg then 6 mg/kg every 3 weeks until there is disease progression...